2760-98-7Relevant articles and documents
Isophthaloyl-Based Selective Fluorescence Receptor for Zn (II) Ion in Semi-Aqueous Medium
Khadke,Patil,Patil,Borhade
, p. 837 - 843 (2019)
A novel Isophthaloyl-based symmetrical (12E,21E)-N1’,N3’-bis(2-hydroxybenzylidene) isophthalohydrazide, receptor (1) was synthesized and characterized using various spectroscopic technique. The reorganization ability of receptor (1) was evaluated in semi-aqueous medium and shows significant enhancement in fluorescence intensity for Zn (II) ion over various metal ions in CH3CN:H2O (1:1, v/v). The 1:2 binding stoichiometry between receptor (1) and Zn (II) ion was established using Job’s plot and the proposed complex structure was calculated by applying Density Functional Theory (DFT) method. The binding constant (Ka) of receptor (1) with Zn (II) ion was established with the Benesi-Hildebrand plot, Scatchard and Connor’s plot and the values are 1.00 × 104?M?1, 1.05× 104?M?1 and 1.05× 104?M?1 respectively. The limit of detection (LOD) and limit of quantification (LOQ) of receptor (1) and Zn (II) ion was 0.292?μM and 0.974?μM respectively. The binding mode was due to photo-induced electron transfer (PET) and the coordination of Zn (II) ion with C = N hydroxyl group of receptor (1). Electrochemical analysis of metal free receptor (1) and with Zn (II) ion also confirmed the formation of complex.
A Strategy to Synthesize Molecular Knots and Links Using the Hydrophobic Effect
Cougnon, Fabien B.L.,Caprice, Kenji,Pupier, Marion,Bauzá, Antonio,Frontera, Antonio
, p. 12442 - 12450 (2018)
Conventional approaches to the synthesis of molecular knots and links mostly rely on metal templation. We present here an alternative strategy that uses the hydrophobic effect to drive the formation of complex interlocked structures in water. We designed an aqueous dynamic combinatorial system that can generate knots and links. In this system, the self-assembly of a topologically complex macrocycle is thermodynamically favored only if an optimum packing of all its components minimizes the hydrophobic surface area in contact with water. Therefore, the size, geometry, and rigidity of the initial building blocks can be exploited to control the formation of a specific topology. We illustrate the validity of this concept with the syntheses of a Hopf link, a Solomon link, and a trefoil knot. This latter molecule, whose self-assembly is templated by halides, binds iodide with high affinity in water. Overall, this work brings a fresh perspective on the synthesis of topologically complex molecules: Solvophobic effects can be intentionally harnessed to direct the efficient and selective self-assembly of knots and links.
FLOW CHEMISTRY SYNTHESIS OF ISOCYANATES
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Paragraph 0175; 0186-0187; 0250; 0253-0254, (2021/06/22)
The disclosure provides, inter alia, safe and environmentally-friendly methods, such as flow chemistry, to synthesize isocyanates, such as methylene diphenyl diisocyanate, toluene diisocyanate, hexamethylene diisocyanate, isophorone diisocyanate, and tetramethylxylene diisocyanate.
Preparation method and application of cobalt organic macro-cyclic compound
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Paragraph 0027; 0028, (2020/06/04)
The invention belongs to the technical field of supramolecular chemistry, and relates to a preparation method and application of a cobalt organic macro-cyclic compound. The preparation method is characterized in that Co in a transition metal cobalt salt is used as a node, L is used as a ligand for reaction to prepare the metal organic macro-cyclic compound, and the synthetic route is as follows: Co+L-> Co-L; wherein the ligand L is selected from DTP; the transition metal cobalt salt is selected from one of cobalt chloride hexahydrate, cobalt nitrate hexahydrate, cobalt sulfate heptahydrate, cobalt tetrafluoroborate hexahydrate or cobalt perchlorate hexahydrate. The prepared cobalt organic macro-cyclic compound is low in raw material price and high in yield. The obtained compound isstable in chemical property, can catalyze an intra-molecular dehydrogenation coupling reaction of N-phenyl enamine, realizes efficient and green dehydrogenation, and has an important realistic meaning.