27610-86-2

Usage

Structure

Cyclic ketone with two cyclopentyl rings linked by a carbonyl group
The compound has a unique structure consisting of two five-membered cyclopentyl rings connected by a carbonyl group (C=O).

Applications

Building block in the synthesis of various organic compounds
The compound is used as a starting material or intermediate in the production of other organic compounds.

Potential Applications

Pharmaceuticals, agrochemicals, and materials science
The compound may have uses in the development of new drugs, agricultural chemicals, and advanced materials.

Biological Activity

Possible potential for biological activity
The compound may have effects on living organisms, making it a subject of interest for further research and development.

Versatility

Valuable in various fields of chemistry and industry
The compound's diverse properties make it useful in a wide range of applications and industries.

Upstream product

• 930-30-3 cyclopent-2-enone 
• 142-29-0 cyclopentene 
• 287-92-3 Cyclopentane 
• 137-43-9 Cyclopentyl bromide 
• 120-92-3 cyclopentanone 
• 542-92-7 cyclopenta-1,3-diene 
• 1700-21-6 3-Trichloracetoxy-1--cyclopentan 
• 2177-65-3 3-Hydroxy-1--cyclopentan 
• 103983-43-3 3-Hydroxy-1-cyclopentyl-cyclopentan 

Relevant academic research and scientific papers

Direct β-Alkylation of Ketones and Aldehydes via Pd-Catalyzed Redox Cascade

We report a direct β-alkylation of ketones and aldehydes with simple alkyl bromides through a Pd-catalyzed redox-cascade strategy. The use of a Cu cocatalyst is important for improved efficiency. The reaction is redox-neutral, without the need for strong acids or bases. Both cyclic and acyclic ketones, as well as α-branched aldehydes, are suitable substrates for coupling with secondary and tertiary alkyl bromides. Concise formal synthesis of Zanapezil is achieved using this β-alkylation method.

Photomediated synthesis of β-alkylketones from cycloalkanes

β-Cycloalkylketones are prepared through a photomediated radical addition reaction onto enones starting from the corresponding alkanes (i.e., cyclopentane, -hexane, -heptane, -dodecane and adamantane). The alkyl radicals are generated via hydrogen abstrac

Copper-Catalyzed Conjugate Additions of Organozirconocenes. Synthetic and Mechanistic Studies.

In the presence of 3-10 mol percent of Cu(I) salts such as CuBr*SMe2 or CuCN, alkylzirconocenes add readily to α,β-unsatuatred ketones, aldehydes, and sulfones.The reaction yield is sensitive to the presence of Lewis acids and bases.Steric hindrance as well as a broad range of functional groups are tolerated in the conjugate addition process.Unsaturated N-acyl oxazolidinones give high diastereoselectivities for the formation of the new asymmetric carbon.The resulting zirconium enolates can be used for tandem aldol addition reactions to aldehydes.Depending on the type of copper salt used, slow or fast formation of copper mirror occurs, but no intermediate copper species is detected spectroscopically.Therefore, a mechanism involving enone complexation by the Lewis-acidic zirconocene followed by inner-spere transfer of the alkyl substituent to chelated Cu(I) is proposed.

Transmetalation Reactions of Alkylzirconocenes: Copper-Catalyzed Conjugate Addition to Enones

Rapid hydrozirconation of alkenes by zirconocene hydrochloride, followed by addition of 1 equiv of enone and catalytic amounts of Cu(I) salts, led to the corresponding 1,4-addition products in moderate to high yields and provided the first protocol for in situ preparation of alkyl cuprates from alkenes.