276244-14-5

Upstream product

• 103174-02-3 (3R,4S)-cis-1-(p-anisyl)-3-acetoxy-4-<(S)-2,2-dimethyl-1,3-dioxolan-4-yl>azetidin-2-one 
• 141781-24-0 [1-((S)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-meth-(E)-ylidene]-(4-methoxy-phenyl)-amine 
• 115828-87-0 (3R,4S)-cis-1-(p-anisyl)-3-hydroxy-4-<(S)-2,2-dimethyl-1,3-dioxolan-4-yl>azetidin-2-one 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 153463-32-2 (S)-4-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(4-methoxyphenyl)azetidine-2,3-dione 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 

Downstream Products

• 1156403-98-3 C₃₅H₃₅NO₇ 
• 1156403-99-4 C₃₆H₃₇NO₇ 
• 1454786-20-9 C₂₁H₂₁NO₅ 
• 1454786-19-6 C₃₂H₂₇NO₄ 
• 1454786-18-5 C₃₁H₂₉NO₅ 
• 1454786-16-3 C₂₄H₂₂BrNO₄ 
• 1454786-15-2 C₂₄H₂₂⁽²⁾HNO₄ 
• 1454786-25-4 C₂₁H₂₁NO₅ 
• 1454786-33-4 C₂₁H₂₁NO₄⁽¹⁸⁾O 
• 1454786-29-8 C₂₁H₁₉NO₄ 
• 1454786-31-2 C₂₉H₂₃NO₄ 
• 1301163-39-2 1-methoxy-4-(3-phenylbut-3-en-1-yn-1-yl)benzene 
• 1454786-28-7 C₂₁H₁₈BrNO₄ 
• 1454786-23-2 C₂₁H₂₀BrNO₅ 

Relevant academic research and scientific papers

Direct allenol-based stereocontrolled access to substituted (E)-1,3-enynes

A stereoselective synthesis of 1-substituted (E)-2-aryl-but-1-en-3-ynes, including tetrasubstituted alkenes, has been developed from aryl-substituted α-allenols by treatment with the AcCl-NaOH (aqueous) system. This transformation might be explained throu

Divergent reactivity of 2-azetidinone-tethered allenols with electrophilic reagents: Controlled ring expansion versus spirocyclization

A dual reactivity of 2-azetidinone-tethered allenols may occur by judicious choice of the electrophilic reagents, namely halogenating versus selenating reagents. Using common substrates, structurally different compounds, namely tetramic acids (from N-bromosuccinimide) or spirocyclic seleno-ss-lactams (from N-phenylselenophthalimide), can be readily synthesized by these divergent protocols.

New regiocontrolled synthesis of functionalized pyrroles from 2-azetidinone-tethered allenols

A new one-pot approach to synthesize densely substituted racemic and enantiopure pyrroles from β-lactams has been developed. The approach relies on the regiocontrolled cyclization of β-allenamine intermediates derived from the ring opening of 2-azetidinon

Diversity-oriented preparation of enantiopure spirocyclic 2-azetidinones from α-oxo-β-lactams through barbier-type reactions followed by metal-catalyzed cyclizations

Novel, simple, and convenient strategies to diversely functionalized spirocyclic β-lactams have been developed by using different metal-mediated carbonyl addition/cyclization reaction sequences. Spirocyclization precursors, 2-azetidinone-tethered homoally

Domino metal-free allene-β-lactam-based access to functionalized pyrroles

A novel transition metal-free domino reaction sequence in allene-β-lactams, leading to the biologically relevant pyrrole frame has been developed using a sodium methoxide-methanol system. The Royal Society of Chemistry 2006.

Metal-assisted synthesis of enantiopure spirocyclic β-lactams from azetidine-2,3-diones

A novel approach to enantiopure spirocyclic β-lactams has been developed by using different intramolecular metal-catalyzed cyclization reactions in monocyclic unsaturated alcohols. A novel approach to enantiopure spirocyclic β-lactams has been developed b

New aspects of the indium chemistry of carbonyl-β-lactams

Reactions of racemic as well as optically pure carbonyl-β-lactams with stabilized organo-indium reagents were investigated in aqueous media. The regio- and stereochemistry of the processes were generally good, offering a convenient asymmetric entry to den

Metal-promoted allylation, propargylation, or allenylation of azetidine-2,3-diones in aqueous and anhydrous media. Application to the asymmetric synthesis of densely functionalized 3-substituted 3-hydroxy-β-lactams

Metal-mediated carbonyl allylation, allenylation, and propargylation of optically pure azetidine-2,3-diones were investigated in both anhydrous and aqueous environments. Different metals promoters showed varied regioselectivities on product formation duri

Regio- and stereocontrolled metal-mediated carbonyl propargylation or allenylation of enantiomerically pure azetidine-2,3-diones: Synthesis of highly functionalized 3-substituted 3-hydroxy-β-lactams

(Matrix presented) Regio-and stereocontrolled metal-mediated Barbier-type reactions of azetidine-2,3-diones with differently substituted propargyl bromides offer an efficient asymmetric entry to densely functionalized 3-propargyl-(or allenyl-) substituted