276248-88-5

Upstream product

• 276248-87-4 (R)-1-Methoxy-4-(4-methoxy-benzyloxy)-butan-2-ol 
• 69831-70-5 (2R)-2-benzyloxy-pent-4-en-1-ol 
• 253450-86-1 (4S)-4-benzyl-3-[(2R)-2-benzyloxy-pent-4-enoyl]-oxazolidin-2-one 
• 236110-81-9 (4S)-4-benzyl-3-[2-(benzyloxy)acetyl]-1,3-oxazolan-2-one 

Downstream Products

• 869382-30-9 (2S,3R,5R)-5-Benzyloxy-1-((S)-4-benzyl-2-thioxo-thiazolidin-3-yl)-3-hydroxy-6-methoxy-2-methyl-hexan-1-one 
• 869382-31-0 (2S,3R,5R)-5-Benzyloxy-6-methoxy-2-methyl-3-triethylsilanyloxy-hexanal 
• 869382-52-5 (2S,3R,5R)-5-Benzyloxy-1-((S)-4-benzyl-2-thioxo-thiazolidin-3-yl)-6-methoxy-2-methyl-3-triethylsilanyloxy-hexan-1-one 
• 869382-29-6 ((3R,4S,5S,6R,8R)-8-Benzyloxy-9-methoxy-3,5-dimethyl-2-oxo-6-triethylsilanyloxy-4-trimethylsilanyloxy-nonyl)-phosphonic acid dimethyl ester 
• 869382-32-1 (2R,3S,4R,5R,7R)-7-Benzyloxy-1-((S)-4-benzyl-2-thioxo-thiazolidin-3-yl)-3-hydroxy-8-methoxy-2,4-dimethyl-5-triethylsilanyloxy-octan-1-one 
• 869382-37-6 Acetic acid (E)-(4S,5S)-8-[(2S,3R,4S,5R,6R)-6-((R)-2-benzyloxy-3-methoxy-propyl)-4-hydroxy-2-methoxy-3,5-dimethyl-tetrahydro-pyran-2-yl]-4-(tert-butyl-dimethyl-silanyloxy)-5-methoxy-oct-7-enyl ester 
• 869382-53-6 (2R,3S,4S,5R,7R)-7-Benzyloxy-1-((S)-4-benzyl-2-thioxo-thiazolidin-3-yl)-8-methoxy-2,4-dimethyl-5-triethylsilanyloxy-3-trimethylsilanyloxy-octan-1-one 
• 869382-47-8 Acetic acid (E)-(4S,5S)-8-[(2S,3R,4S,5S,6R)-6-((R)-2-benzyloxy-3-methoxy-propyl)-4-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-3,5-dimethyl-tetrahydro-pyran-2-yl]-4-(tert-butyl-dimethyl-silanyloxy)-5-methoxy-oct-7-enyl ester 
• 869382-38-7 acetic acid 6-{5-[6-(2-benzyloxy-3-methoxy-propyl)-4-(tert-butyl-dimethyl-silanyloxy)-2-methoxy-3,5-dimethyl-tetrahydro-pyran-2-yl]-2-oxo-[1,3]dioxolan-4-yl}-4-(tert-butyl-dimethyl-silanyloxy)-5-methoxy-hexyl ester 
• 869382-36-5 Acetic acid (E)-(4S,5S,10R,11S,12S,13R,15R)-15-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-5,16-dimethoxy-10,12-dimethyl-9-oxo-13-triethylsilanyloxy-11-trimethylsilanyloxy-hexadec-7-enyl ester 

Relevant academic research and scientific papers

Enantioselective synthesis of apoptolidinone: Exploiting the versatility of thiazolidinethione chiral auxiliaries

An efficient, enantioselective synthesis of apoptolidinone has been completed, demonstrating the versatility of thiazolidinethione auxiliaries. Three propionate aldol additions and two asymmetric glycolate alkylations function to establish 8 of the 12 ste

Synthesis of the apoptosis inducing agent apoptolidin. Assembly of the C(16)-C(28) fragment.

[reaction--see text] A stereoselective synthesis of the C(16)-C(28) fragment of the apoptosis inducing agent apoptolidin is described. Key steps include two propionate aldol reactions and a stereoselective Mukaiyama aldol addition of enolsilane 19 to beta