27648-87-9Relevant articles and documents
The synthesis of macrocyclic diamides and tetramides containing phenol units
Gryko, Daniel T.,Piatek, Piotr,Jurczak, Janusz
, p. 7957 - 7966 (1997)
Thirteen new macrocyclic diamides and tetramides have been synthesized by reaction of methyl phenoxyacetates (readily obtained from various phenols) with α,ω-diamines in methanol as a solvent. Relationship between structure of esters and ratio of diamides to tetraamides has been investigated.
Guanidino substituted isoindolones as novel glycoprotein IIb-IIIa receptor antagonists
Lal, Bansi,Gangopadhyay, Ashok K.,Jagtap,Tanpure, Rajendra,Rao,Gupte, Ravindra D.,Subbarayan,Asudani, Gope
, p. 1815 - 1832 (2008/09/18)
Design and synthesis of a novel potent glycoprotein IIb-IIIa (GP IIb-IIIa) receptor antagonist based on isoindolone skeleton has been described. This scaffold has been derived from earlier reported pseudopeptides. Synthesis by a novel route has been achieved. Few molecules show very potent in vitro activity. Further identification of probable additional hydrogen bond donor site has been described.
Iodinated biaryls synthesized by the direct dehydrodimerization of iodoarenes using phenyliodine(III) bis(trifluoroacetate) (PIFA)
Mirk, Daniela,Willner, Alexander,Froehlich, Roland,Waldvogel, Siegfried R.
, p. 675 - 681 (2007/10/03)
Multiply iodinated biaryls can be prepared in yields up to 75% by direct oxidative coupling reaction of the iodinated arenes. The PIFA-mediated dehydrodimerization is superior to all other known methods. The developed protocol is reliable and easy to perform.