27652-22-8 Usage
Uses
Used in Pharmaceutical Industry:
Arbusculin A is used as a pharmaceutical agent for its inhibitory activity against melanogenesis. This property makes it a potential candidate for the treatment of hyperpigmentation disorders and other conditions related to excessive melanin production.
Used in Cosmetic Industry:
In the cosmetic industry, arbusculin A is used as an active ingredient in skin care products for its ability to inhibit melanogenesis. This can help reduce the appearance of dark spots, age spots, and other pigmentation issues, promoting a more even skin tone.
Used in Research Applications:
Arbusculin A is also used in research settings to study the mechanisms of melanogenesis and the development of new treatments for pigmentation-related conditions. Its inhibitory activity against melanogenesis makes it a valuable tool for understanding the underlying processes and identifying potential therapeutic targets.
Check Digit Verification of cas no
The CAS Registry Mumber 27652-22-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,6,5 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 27652-22:
(7*2)+(6*7)+(5*6)+(4*5)+(3*2)+(2*2)+(1*2)=118
118 % 10 = 8
So 27652-22-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H22O3/c1-9-10-5-8-14(2)6-4-7-15(3,17)12(14)11(10)18-13(9)16/h10-12,17H,1,4-8H2,2-3H3/t10-,11-,12+,14+,15+/m0/s1
27652-22-8Relevant academic research and scientific papers
Partial Synthesis of Sesquiterpene Lactones: A Route to 7,11-Ene-13-hydroxyeudesmanolides
Collado, Gonzales,Madero, J. Gomez,Massanet, G. Martinez,Luis, F. Rodriguez
, p. 3587 - 3591 (2007/10/02)
An efficient partial synthesis of several sesquiterpene lactones has been carried out from costunolide by treatment with trimethyl(phenyl)ammonium perbromide.A selective bromination at the C-11 =C-13 bond provides a new route to 7,11-ene-13-hydroxyeudesmanolides.A synthesis of arbuscolin D has been achieved.
Chemistry of costunolide and biological activity of the derived lactones
Kalsi,Khurana, Sarita,Talwar
, p. 103 - 109 (2007/10/02)
Costunolide and its derived C-16 germacranolides on oxidation with selenium dioxide-t-butyl hydroperoxide afforded two melampolides, an aldehydolactone and the corresponding hydroxylactone, in each case. Structures were assigned to these melampolides on the basis of spectral data and chemical correlation. The aldehydolactones were significantly more active root promotors than their parent lactones. Costunolide and related germacranolides underwent cyclization on treatment with iodine and pyridinium chlorochromate to afford interesting products. (-)-β-Frullanolide has been synthesized and shown to be biologically more active when compared with its parent trans-lactone.
