27664-19-3Relevant academic research and scientific papers
Synthesis and biological evaluation of novel indole-pyrazoline hybrid derivatives as potential topoisomerase 1 inhibitors
Shu, Bing,Yu, Qian,Hu, De-xuan,Che, Tong,Zhang, Shang-shi,Li, Ding
, (2020)
A series of novel indole-pyrazoline hybrid derivatives were designed, synthesized, and evaluated for topoisomerase 1 (Top1) inhibitory activity. Top1-mediated relaxation assays showed that our synthesized compounds had variable Top1 inhibitory activity. A
