276691-69-1Relevant articles and documents
Synthesis of N-aryl substituted 4H-1,4-benzothiazine 1,1-dioxide 2-carboxylic acid-esters
Lopez, Simon E.,Charris, Jaime,Urdaneta, Neudo,Lobo, Gricela
, p. 53 - 61 (1998)
A group of N-aryl substituted 1,4-benzothiazine-1,1-dioxide-2 carboxylic acid esters is reported. This is the first example of N-aryl-derivatives of the 4H-1,4-benzothiazine nucleus; the key step is the cyclization of N-aryl-phenylsulfonyl-acrylates 4-8 using potassium carbonate in acetonitrile/18-crown-6-ether to the corresponding title compounds in moderate yields.