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27682-64-0

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27682-64-0 Usage

General Description

5-CHLORO-2-ETHOXYBENZALDEHYDE, also known as 5-chloro-2-ethoxybenzaldehyde, is a chemical compound with the molecular formula C9H9ClO2. It is a pale yellow liquid with a strong, sweet, floral odor. 5-CHLORO-2-ETHOXYBENZALDEHYDE is commonly used in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is also used as a building block in the synthesis of various organic compounds. In addition, 5-CHLORO-2-ETHOXYBENZALDEHYDE exhibits antimicrobial properties and has potential applications in the development of antimicrobial agents. However, it is important to handle this chemical with care, as it may cause irritation to the skin, eyes, and respiratory system.

Check Digit Verification of cas no

The CAS Registry Mumber 27682-64-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,6,8 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 27682-64:
(7*2)+(6*7)+(5*6)+(4*8)+(3*2)+(2*6)+(1*4)=140
140 % 10 = 0
So 27682-64-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H9ClO2/c1-2-12-9-4-3-8(10)5-7(9)6-11/h3-6H,2H2,1H3

27682-64-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-chloro-2-ethoxybenzaldehyde

1.2 Other means of identification

Product number -
Other names 5-Chloro-2-ethoxy-benzaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:27682-64-0 SDS

27682-64-0Relevant articles and documents

Synthesis and bioevaluation of substituted chalcones, coumaranones and other flavonoids as anti-HIV agents

Cole, Amy L.,Hossain, Sandra,Cole, Alex M.,Phanstiel, Otto

, p. 2768 - 2776 (2016/06/08)

A series of chalcone, flavone, coumaranone and other flavonoid compounds were screened for their anti HIV-1 activity in two cell culture models using TZM-bl and PM1 cells. Within the systems evaluated, the most promising compounds contained either an α- or β-hydroxy-carbonyl motif within their structure (e.g., 8 and 9). Efficacious substituents were identified and used to design new HIV inhibitors with increased potency and lower cytotoxicity. Of the scaffolds evaluated, specific chalcones were found to provide the best balance between anti-HIV potency and low host cell toxicity. Chalcone 8l was shown to inhibit different clinical isolates of HIV in a dose-dependent manner (e.g., IC50 typically ≤ 5 μM). Inhibition of HIV infection experiments using TZM-bl cells demonstrated that chalcone 8l and flavonol 9c had IC50 values of 4.7 μM and 10.4 μM, respectively. These insights were used to design new chalcones 8o and 8p. Rewardingly, chalcones 8o and 8p (at 10 μM) each gave >92% inhibition of viral propagation without impacting PM1 host cell viability. Inhibition of viral propagation significantly increased (60-90%) when PM1 cells were pre-incubated with chalcone 8o, but not with the related flavonol 9c. These results suggested that chalcone 8o may be of value as both a HIV prophylactic and therapy. In summary, O-benzyl-substituted chalcones were identified as promising anti-HIV agents for future investigation.

Hypoglycemic 5-substituted oxazolidine-2,4-diones

-

, (2008/06/13)

Hypoglycemic 5-phenyl and 5-naphthyl oxazolidine-2,4-diones and the pharmaceutically-acceptable salts thereof; certain 3-acylated derivatives thereof; a method of treating hyperglycemic animals therewith; and intermediates useful in the preparation of said compounds.

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