27685-90-1

Usage

Uses

Used in Chemical Synthesis:
2,3-dihydro-2-oxobenzoxazole-6-sulphonyl chloride is used as a key intermediate for the synthesis of various chemical substances due to its reactive sulphonyl chloride group and unique aromatic heterocyclic structure.
Used in Dye Manufacturing:
2,3-dihydro-2-oxobenzoxazole-6-sulphonyl chloride is used as a chemical building block for the production of dyes, contributing to the development of new colorants with specific properties.
Used in Pharmaceutical Industry:
2,3-dihydro-2-oxobenzoxazole-6-sulphonyl chloride is used as a starting material or a reagent in the synthesis of pharmaceutical compounds, facilitating the creation of new drugs with potential therapeutic applications.
Used in Agricultural Products:
2,3-dihydro-2-oxobenzoxazole-6-sulphonyl chloride is used as a component in the formulation of agricultural products, such as pesticides or herbicides, due to its ability to interact with other chemicals to form new substances with desired properties.
Used in Organic Chemistry Research:
2,3-dihydro-2-oxobenzoxazole-6-sulphonyl chloride is used as a research tool in organic chemistry, allowing scientists to explore its reactivity and potential applications in the synthesis of complex organic compounds.

InChI:InChI=1/C7H4ClNO4S/c8-14(11,12)4-1-2-5-6(3-4)13-7(10)9-5/h1-3H,(H,9,10)

Upstream product

• 59-49-4 2-Benzoxazolinone 
• 5329-14-6 aminosulfonic acid 

Downstream Products

• 78324-72-8 2-oxo-2,3-dihydro-benzoxazole-6-sulfonic acid anilide 
• 22876-18-2 2-oxo-2,3-dihydro-benzooxazole-6-sulfonic acid amide 
• 1393726-92-5 6-(4-(4-acetylphenyl)piperazin-1-ylsulfonyl)benzo[d]oxazol-2(3H)-one 
• 1450923-57-5 C₁₄H₁₁ClN₄O₃S₂ 
• 1450923-55-3 N-(2,4-dimethoxybenzyl)-2-oxo-N-(1,3,4-thiadiazol-2-yl)-2,3-dihydrobenzo[d]oxazole-6-sulfonamide 
• 1450923-56-4 3-(3-chlorophenyl)-N-(2,4-dimethoxybenzyl)-2-oxo-N-(1,3,4-thiadiazol-2-yl)-2,3-dihydrobenzo[d]oxazole-6-sulfonamide 
• 1607485-75-5 N-(2,4-dimethoxybenzyl)-N-(6-fluoropyridin-2-yl)-2-oxo-2,3-dihydrobenzo[d]oxazole-6-sulfonamide 
• 1432514-50-5 N-(2,4-dimethoxybenzyl)-2-oxo-N-(1,2,4-thiadiazol-5-yl)-2,3-dihydro-1,3-benzoxazole-6-sulfonamide 
• 1373829-76-5 2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl-sulfonyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid 

Relevant academic research and scientific papers

Benzazoles. 4.* Synthesis and chemical reactions of 6-chlorosulfonylbenzoxazolin-2-ones

The corresponding 6-chlorosulfonyl derivatives were synthesized from benzoxazolin-2-one and its 3-methyl derivative by treatment with chlorosulfonic acid. By treatment of the compounds obtained with water and other nucleophilic reagents (aliphatic and heterocyclic amines) 2-oxobenzoxazoline-6-sulfonic acids and a series of their amides were obtained, while reduction with SnCl 2?2H2O gave 6-mercaptobenzoxazolin-2-ones.

ALKYL-SUBSTITUTED 3' COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein R1, R2, Ar, m and n are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

CONDENSED HETEROCYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I) wherein R1, A, B, D, E, G, Q, Ar, n, m, and p are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

ACYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein R1, R2, R5, Q, G, Ar, m, and n are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): formula (I) wherein Cy is selected from formula (Il) and wherein R1, R2, R3, Q, G, Ar, m, n and p are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

PYRROLIDINE-SUBSTITUTED AZAINDOLE COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein R1, R2, A, B, D, E, G, Ar, and n are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

3' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein Q, R1, R4, m and Ar are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5HT6 receptor which are of the formula (I), wherein R1-R3 A, B, D, E, G, Q, and x are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

Process for the preparation of aromatic sulfonyl chlorides

A process for the preparation of aromatic sulfonyl chlorides of the formula I STR1 in which R1, R2 and R3 are identical or different and are hydrogen, fluorine, chlorine, bromine or iodine atoms, alkyl(C1 -C4), acetamido, nitro or carboxyl groups, or R1 and R2 together form an aromatic or heteroaromatic ring having 5 or 6 ring members, which can be substituted by fluorine, chlorine, bromine or iodine atoms, alkyl(C1 -C4), acetamido, nitro or carboxyl groups, by reaction of aromatic compounds of the formula II STR2 in which R1, R2 and R3 have the abovementioned meanings, with chlorosulfonic acid in excess or with chlorosulfonic acid or oleum and thionyl chloride, by reacting in the presence of sulfamic acid as a catalyst.