27687-13-4

Basic information

• Product Name: Carbamic acid, [[4-(chlorocarbonyl)cyclohexyl]methyl]-, phenylmethyl ester, trans-
• CAS NO: 27687-13-4
• Molecular Formula: C16H20ClNO3
• Molecular Weight: 309.793
• Mol File: 27687-13-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [[4-(chlorocarbonyl)cyclohexyl]methyl]-, phenylmethyl ester, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [[4-(chlorocarbonyl)cyclohexyl]methyl]-, phenylmethyl ester, trans-(27687-13-4)
• EPA Substance Registry System: Carbamic acid, [[4-(chlorocarbonyl)cyclohexyl]methyl]-, phenylmethyl ester, trans-(27687-13-4)

Safety Data

• Hazardous Substances Data: 27687-13-4(Hazardous Substances Data)

Upstream product

• 27687-12-3 4-(Benzyloxycarbonylamino-methyl)-cyclohexanecarboxylic acid 
• 501-53-1 benzyl chloroformate 
• 1197-18-8 trans-4-aminomethyl-cyclohexyl-carboxylic acid 
• 27687-12-3 (1r,4r)-4-({[(benzyloxy)carbonyl]amino}methyl)cyclohexane-1-carboxylic acid 

Downstream Products

• 103892-17-7 ((S)-5-(4-Acetyl-phenylcarbamoyl)-5-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-pentyl)-carbamic acid benzyl ester 
• 138884-66-9 ((S)-7-(4-Benzoyl-phenoxy)-5-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-6-oxo-heptyl)-carbamic acid tert-butyl ester 
• 138848-86-9 [(S)-5-{[4-(Benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-6-(3,4-dihydro-2H-quinolin-1-yl)-6-oxo-hexyl]-carbamic acid benzyl ester 
• 138865-32-4 [(S)-5-{[4-(Benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-5-(4-nitro-phenylcarbamoyl)-pentyl]-carbamic acid benzyl ester 
• 138848-87-0 [(S)-5-{[4-(Benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-5-(5,6,7,8-tetrahydro-naphthalen-2-ylcarbamoyl)-pentyl]-carbamic acid benzyl ester 
• 138848-88-1 4-((S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoylamino)-benzoic acid methyl ester 
• 138848-85-8 [(S)-5-{[4-(Benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-6-(4-benzyl-piperidin-1-yl)-6-oxo-hexyl]-carbamic acid benzyl ester 
• 138848-90-5 ((S)-4-(4-Benzoyl-phenylcarbamoyl)-4-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-butyl)-carbamic acid benzyl ester 
• 138848-94-9 (S)-6-Benzyloxycarbonylamino-2-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-hexanoic acid 4-benzoyl-phenyl ester 
• 138848-98-3 ((S)-7-(4-Benzoyl-phenoxy)-5-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-6-oxo-heptyl)-carbamic acid benzyl ester 
• 138848-97-2 ((S)-7-(4-Benzoyl-phenylamino)-5-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-6-oxo-heptyl)-carbamic acid benzyl ester 
• 138921-48-9 ((R)-5-(4-Benzoyl-phenylcarbamoyl)-5-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-pentyl)-carbamic acid benzyl ester 
• 138848-77-8 ((S)-5-(4-Benzoyl-phenylcarbamoyl)-5-{[4-(benzyloxycarbonylamino-methyl)-cyclohexanecarbonyl]-amino}-pentyl)-carbamic acid benzyl ester 
• 140135-41-7 C₂₄H₃₇N₇O₆ 

Relevant articles and documents

Discovery and evaluation of a series of 3-acylindole imidazopyridine platelet-activating factor antagonists

Studies conducted with the goal of discovering a second-generation platelet-activating factor (PAF) antagonist have identified a novel class of potent and orally active antagonists which have high aqueous solubility and long duration of action in animal m

Indole-3-carbonyl and indole-3-sulfonyl imidazo[4,5-c]pyridine derivatives as platelet activating factor antagonists.

-

Development of selective inhibitors against plasma kallikrein

Specific plasma kallikrein inhibitors were designed and synthesized and their structure-activity relationship was studied. trans-4-Aminomethylcyclohexanecarbonyl(Tra)-lysyl-4-ethoxycarbonylanili de inhibited plasma kallikrein and plasmin with 1C50/s