276870-26-9Relevant academic research and scientific papers
Megastigmanes from the aerial part of Euphorbia heterophylla
Thapsut, Monnapa,Singha, Suriphon,Seeka, Chonticha,Sutthivaiyakit, Somyote
, p. 42 - 47 (2021)
Three unprecedented megastigmanes together with twelve known compounds were isolated from the aerial part of Euphorbia heterophylla. The structural elucidation was based on extensive uses of spectroscopic data. The absolute configuration assignment of 1 was based on NOESY correlations and comparison of the experimental and calculated ECD spectra. Selected isolates obtained in sufficient quantity were evaluated for their cytotoxic activity.
Stereochemistry of megastigmane glucosides from Glochidion zeylanicum and Alangium premnifolium
Otsuka, Hideaki,Hirata, Eiji,Shinzato, Takakazu,Takeda, Yoshio
, p. 763 - 768 (2007/10/03)
From Glochidion zeylanicum, two megastigmane glucosides, 3- and 9-O-β-D-glucopyranosides of (3S,5R,6R,7E,9S)-megastigman-7-ene-3,5,6,9-tetrol (1 and 2, respectively), were isolated. Their structures were different from those of kiwiionoside (3) and actinidioionoside (4), isolated from Actinidia chinensis and Actinidia polygama, respectively, in the stereochemistry at the 9-positions. Alangionosides E (5) and O (6), isolated from the leaves of Alangium premnifolium, are also megastigmane glucosides, and the latter is closely related to 1 and actinidioionoside (4). However, the absolute configurations of the 9-position remained to be determined. They were analyzed to be R by means of a modified Mosher's method. Alangionoside E (5) is identical with corchoionoside A in all aspects. The name of corchoionoside A must be retained thereafter.
