27699-94-1Relevant academic research and scientific papers
HEAT SHOCK PROTEIN 90 INHIBITORS, METHODS OF PREPARING SAME, AND METHODS FOR THEIR USE
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Page/Page column 14, (2010/04/28)
Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors are disclosed. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases and conditions, such as inflammation and neurodegenerative disorders. Methods of treating and preventing cancer and other Hsp90 related diseases and conditions are disclosed that include administering to the subject a therapeutically effective amount of an Hsp90 inhibitor. Methods of preparing the novel Hsp90 inhibitors are also provided.
CATALYTIC TRANSAMINATION OF DIALKYLAMINO-o-QUINONES
Tsizin, Yu. S.,Chernyak, S. A.,Kornienko, N. I.
, p. 2381 - 2388 (2007/10/02)
The ions of transition and alkaline-earth metals catalyze the transamination of bicyclic dialkylamino-o-quinones by primary and secondary amines.The effectiveness of the catalysis is determined by the type of chelate complex formed by the o-quinones and b
