2772-60-3Relevant articles and documents
Rapid and efficient synthesis of N-alkylbenzamides under microwave irradiation
Cermak, Jan K.,Kolar, Karel,Cirkva, Vladimir
, p. 126 - 130 (2013)
The microwave-assisted synthesis of N-alkylbenzamides from benzoic acid and primary aliphatic amines has been developed under solvent-free conditions. The different solid catalysts have been investigated. The suggested synthesis is environmentally friendly and excellent yields (97-99 %) have been reached.
Method for preparing amide compound by photocatalysis of organic amine
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Paragraph 0040-0041, (2021/06/06)
The invention relates to the technical field of organic synthesis, in particular to a method for preparing amide compounds through photocatalysis of organic amine. The preparation method comprises the following steps: mixing tetrahalomethane with a solvent, sequentially adding an amine compound, a catalyst and organic carboxylic acid, performing stirring and reacting under an oxygen-containing atmosphere and an illumination condition, and performing separating and purifying to obtain the amide compound with a structure shown in formulas V-VII. According to the method, the reaction is carried out in the air atmosphere under the illumination condition at room temperature and normal pressure, the reaction condition is mild, the raw material source is wide, the cost is low, the byproduct generated after the reaction is the halogen simple substance, the added value is high, a large amount of waste is avoided, and the method has higher atom economy and environmental friendliness and is beneficial to large-scale production.
Effect of Precatalyst Oxidation State in C-N Cross-Couplings with 2-Phosphinoimidazole-Derived Bimetallic Pd(I) and Pd(II) Complexes
Martinez, Erin E.,Moreno, Mariur Rodriguez,Barksdale, Caleb A.,Michaelis, David J.
supporting information, p. 2763 - 2767 (2021/08/27)
We report the catalytic activity of two phosphinoimidazole-derived bimetallic palladium complexes in Pd-catalyzed amination reactions. Our studies demonstrate that the starting oxidation state (Pd(I) or Pd(II)) of the dimeric complex has a significant effect on the efficiency of the catalytic reaction. The corresponding Pd(I) complex shows higher reactivity in Buchwald-Hartwig aminations, while the Pd(II) complex is much more reactive in carbonylative amination reactions. These new dimeric palladium complexes provide good to excellent reactivity and yields in the amination reactions tested.
