277308-30-2

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 41381-89-9 2-(4-phenylthiazol-2-yl)acetonitrile 

Downstream Products

• 277308-39-1 5-cyano-1-phenyl-5-(4-phenyl-thiazol-2-yl)-4-p-tolyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 277308-34-6 2,5-diphenyl-3-(4-phenyl-thiazol-2-yl)-4-p-tolyl-3,4-dihydro-2H-pyrazole-3-carbonitrile 
• 277308-40-4 5-cyano-1-phenyl-5-(4-phenyl-thiazol-2-yl)-4-p-tolyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid phenylamide 

Relevant academic research and scientific papers

Reactions with hydrazonoyl halides XIX1: Synthesis of some pyrazole and 5-arylazothiazole derivatives

Hydrazonoyl chlorides 1 reacted with 2-aryl-1-cyano-1-thiazol-2-ylethenes 2 in presence of triethylamine to give the cycloadducts 4. which were converted to the corresponding pyrazoles 5 by the action of sodium methoxide. The reaction of hydrazonoyl halides 1 and 6 with each of 2-arylidene-2-cyanoethanethioamides 7 and 2-arylhydrazono-2-cyanoethanethioamides 14 in ethanolic triethylamine or ethanolic sodium hydroxide solutions, has been investigated. Structures of all the products were established on the basis of their spectral data and alternative synthesis.