277330-29-7Relevant academic research and scientific papers
SIMULTANEOUS IMAGING OF CARDIAC PERFUSION AND A VITRONECTIN RECEPTOR TARGETED IMAGING AGENT
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, (2008/06/13)
The present invention describes a method of concurrent imaging in a mammal comprising: a) administering to said mammal a vitronectin receptor targeted imaging agent and a perfusion imaging agent; and b) concurrently detecting the vitronectin receptor targ
Disubstituted indazoles as potent antagonists of the integrin α(v)β3
Batt, Douglas G.,Harlow, Patricia P.,Barbera, Frank A.,Spitz, Susan M.,Wexler, Ruth R.,Jadhav, Prabhakar K.,Petraitis, Joseph J.,Houghton, Gregory C.,Modi, Dilip P.,Cain, Gary A.,Corjay, Martha H.,Mousa, Shaker A.,Bouchard, Peter J.,Forsythe, Mark S.
, p. 41 - 58 (2007/10/03)
A new series of indazole-containing α(v)β3 integrin antagonists is described. Starting with lead compound 18a, variations in a number of structural features were explored with respect to inhibition of the binding of β3-transfected 29
