27743-90-4Relevant academic research and scientific papers
Synthesis of 6-Substituted Piperidin-3-ones via Rh(II)-Catalyzed Transannulation of N-Sulfonyl-1,2,3-triazoles with Electron-Rich Aromatic Nucleophiles
Li, Yang,Zhang, Ran,Ali, Arshad,Zhang, Jing,Bi, Xihe,Fu, Junkai
supporting information, p. 3087 - 3090 (2017/06/23)
A highly diastereoselective rhodium(II)-catalyzed transannulation of aldehyde-tethered N-sulfonyl triazoles with electron-rich aromatic nucleophiles is reported for the first time to afford functionalized 6-substituted piperidin-3-ones. The reaction has a broad substrate scope including both aliphatic and aromatic N-sulfonyl-1,2,3-triazoles together with various aromatic nucleophiles. The addition of a catalytic amount of Lewis acid has proven to be crucial for the yield improvement. By employing this methodology, hardly accessible piperidin-3-ones bearing quaternary carbons could be obtained.
Relative asymmetric induction in the intramolecular reaction between alkynes and cyclopropylcarbene-chromium complexes: Stereocontrolled synthesis of five-membered rings fused to oxygen heterocycles
Yan,Zhu,Matasi,Herndon
, p. 1291 - 1301 (2007/10/03)
Synthesis of cyclopentenone derivatives fused to oxygen heterocycles by means of the intramolecular coupling of alkynes and cyclopropylcarbene- chromium complexes has been examined for a variety of cases in which the tethering chain features a stereogenic
