27750-13-6

Basic information

• Product Name: HYDROXYCITRIC ACID LACTONE, (-)-(P)
• Synonyms: HYDROXYCITRIC ACID LACTONE, (-)-(P);3-C-Carboxy-2-deoxy-D-erythropentaric acid 1,4-lactone;Garcinia lactone;(2S,3S)-3-Hydroxy-5-oxotetrahydrofuran-2,3-dicarboxylic acid
• CAS NO: 27750-13-6
• Molecular Formula: C₆H₆O₇
• Molecular Weight: 190.106
• Mol File: 27750-13-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 673.6±55.0 °C(Predicted)
• Appearance: /
• Density: 1.976
• PKA: 2.40±0.40(Predicted)
• CAS DataBase Reference: HYDROXYCITRIC ACID LACTONE, (-)-(P)(CAS DataBase Reference)
• NIST Chemistry Reference: HYDROXYCITRIC ACID LACTONE, (-)-(P)(27750-13-6)
• EPA Substance Registry System: HYDROXYCITRIC ACID LACTONE, (-)-(P)(27750-13-6)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 27750-13-6(Hazardous Substances Data)

Usage

Description

HYDROXYCITRIC ACID LACTONE, (-)-(P) is a naturally occurring compound derived from the Garcinia gardneriana plant. It is characterized by its antiproliferative and antioxidant properties, making it a potential candidate for various applications in the pharmaceutical and health industries.

Uses

Used in Pharmaceutical Industry:
HYDROXYCITRIC ACID LACTONE, (-)-(P) is used as a therapeutic agent for its antiproliferative properties, which can help in inhibiting the growth of cancer cells. This makes it a promising candidate for the development of new cancer treatments.
Used in Health and Nutrition Industry:
HYDROXYCITRIC ACID LACTONE, (-)-(P) is used as a dietary supplement for its antioxidant effects, which can help protect the body from oxidative stress and support overall health.
Used in Cosmetic Industry:
Due to its antioxidant properties, HYDROXYCITRIC ACID LACTONE, (-)-(P) can also be used in the cosmetic industry as an ingredient in skincare products to help protect the skin from environmental damage and promote a healthier, more youthful appearance.

Upstream product

• 469-72-7 (+/-)-3t-hydroxy-5-oxo-tetrahydro-furan-2r,3c-dicarboxylic acid 

Downstream Products

• 4272-10-0 (+/-)-3c-hydroxy-5-oxo-tetrahydro-furan-2r,3t-dicarboxylic acid dimethyl ester 
• 469-72-7 (2S,3R)-tetrahydro-3-hydroxy-5-oxo-2,3-furandicarboxylic acid 
• 4272-10-0 (+/-)-3t-hydroxy-5-oxo-tetrahydro-furan-2r,3c-dicarboxylic acid dimethyl ester 
• 42217-19-6 -1,2-dihydroxy-1,2,3-propanetricarboxylic acid trimethyl ester 
• 4272-10-0 dimethyl (2S,3S)-tetrahydro-3-hydroxy-5-oxo-2,3-furandicarboxylate 
• 460745-68-0 diisopropyl (2S,3S)-tetrahydro-3-hydroxy-5-oxo-2,3-furandicarboxylate 
• 460745-69-1 Acetic acid (3aS,6aS)-5-benzyl-2,4,6-trioxo-hexahydro-furo[2,3-c]pyrrol-3a-yl ester 
• 600121-17-3 Acetic acid (3aS,6aS)-5-[2-(3,4-dimethoxy-phenyl)-ethyl]-2,4,6-trioxo-hexahydro-furo[2,3-c]pyrrol-3a-yl ester 
• 460745-70-4 Acetic acid (3aS,6aS)-5-(4-methoxy-benzyl)-2,4,6-trioxo-hexahydro-furo[2,3-c]pyrrol-3a-yl ester 
• 600121-18-4 (3aS,6aS)-5-benzyl-3a-hydroxydihydro-2H-furo[2,3-c]pyrrole-2,4,6(3H,5H)-trione 
• 600121-23-1 (3aS,6aS)-5-(3,4-dimethoxyphenethyl)-3a-hydroxydihydro-2H-furo[2,3-c]pyrrole-2,4,6(5H,6aH)-trione 

Relevant articles and documents

HIGH PURITY (-) HYDROXYCITRIC ACID METAL SALT DERIVATIVES AND METHOD OF PREPARATION OF THE SAME

The present invention relates to high purity (-) Hydroxycitric acid metal salt derivatives of more than 98% purity having formula Il (a-e), lla; X, 2X = Na Mb; X, 2X= K Hc; X = K, Y = Ca Hd1 X= Na, Y = Ca He; X= 1 /2 Mg, Y = Mg and the method of preparation of high purity (-) hydroxycitric acid metal salt derivatives from (-) hydroxycitric acid lactone having formula (1 ) which in turn is isolated in a simple and efficient manner from dried rinds of the fruits of Garcinia species. This invention employes the HPLC method and optical rotation in assessing the purity (-) hydroxycitric acid and corresponding lactone (1 ).