27768-36-1Relevant academic research and scientific papers
Reversible Aromaticity Transfer in a Bora-Cycle: Boron-Ligand Cooperation
Gellrich, Urs,Diskin-Posner, Yael,Shimon, Linda J. W.,Milstein, David
, p. 13307 - 13313 (2016)
Aromaticity is a central concept in chemistry. Reaction pathways involving reversible ligand dearomatization sequences emerged as a powerful tool for bond activation by metal complexes. Exploring this concept with a metal-free system, we have synthesized
Copper-catalyzed benzylic oxidation of C(sp3)-H bonds
Zhang, Bo,Zhu, Shou-Fei,Zhou, Qi-Lin
supporting information, p. 2033 - 2037 (2013/03/13)
A selective oxidation of benzylic C(sp3)-H bonds to C(sp 3)-O bonds catalyzed by copper complexes of quinoline-imine ligands was developed with peresters as oxidants under mild reaction conditions, which converted benzylic methylenes directly into benzylic alcohols and esters by means of direct C-H bond functionalization.
Group 4 metal bis(chelate) complexes of 2-anilidomethylpyridine ligands: Synthesis and catalytic activity for olefin polymerization
Annunziata, Liana,Li, Gang,Pellecchia, Claudio
experimental part, p. 1 - 8 (2011/04/24)
A series of monoanionic, bidentate 2-anilidomethylpyridine ligands were synthesized and used to prepare bis(chelate) Zr(IV) and Hf(IV) bis(dimethylamido) complexes. All complexes were characterized by NMR spectroscopy and elemental analysis. The solution structures of the complexes were more or less fluxional, depending on the substituent on the ligands. The complexes were tested as catalysts for the polymerization of ethylene and propene, in combination with different activators. Use of AliBu 2H - methylaluminoxane as the co-catalyst resulted in the generation of catalysts producing high molecular weight polyethylenes with good activities, but yielding only stereoirregular and poorly regioregular polypropylenes.
Design and synthesis of noncompetitive metabotropic glutamate receptor subtype 5 antagonists
Kulkarni, Santosh S.,Nightingale, Barbara,Dersch, Christina M.,Rothman, Richard B.,Newman, Amy Hauck
, p. 3371 - 3375 (2007/10/03)
A series of diaryl amides was designed and synthesized as novel nonethynyl mGluR5 antagonists. The systematic variation of the pharmacophoric groups led to the identification of a lead compound that demonstrated micromolar affinity for the mGluR5. Further optimization resulted in compounds with improved binding affinities and antagonist profiles, in vitro.
