277753-38-5Relevant academic research and scientific papers
2-Aryl-5-epoxynitrile anion cyclizations : Total syntheses of (±)-α-cuparenone and (±)-epilaurene
Avila-Zarraga, J. Gustavo,Maldonado, Luis A.
, p. 512 - 513 (2000)
Total syntheses of the cyclopentane sesquiterpenes of the title using an epoxynitrile anion cyclization reaction as key step, are described. The preferential formation of the cyclopentane ring from a terminal disubstituted 5-epoxynitrile (e.g. 2b) had not previously been observed. The 2-aryl substituent is reasonably assumed to be responsible for this divergence.
