277756-45-3 Usage
Uses
Used in Organic Synthesis:
1-Trifluoromethylcyclobutane-1-carboxylic acid serves as a valuable building block in organic synthesis, enabling the creation of new molecules with potential applications across various fields. Its unique structural features make it a versatile component in the synthesis of complex organic compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-trifluoromethylcyclobutane-1-carboxylic acid is utilized for its potential to enhance the biological activity of molecules. The trifluoromethyl group can impart specific properties to molecules, such as increased lipophilicity or metabolic stability, which are crucial for drug discovery and development. This makes the compound an essential tool for designing and optimizing pharmaceutical agents with improved efficacy and safety profiles.
Used in Drug Discovery:
1-TRIFLUOROMETHYLCYCLOBUTANE-1-CARBOXYLIC ACID plays a significant role in drug discovery, where its incorporation into molecular structures can lead to the development of novel therapeutic agents. The unique properties of the trifluoromethyl group, combined with the cyclobutane ring's steric and strained characteristics, can result in molecules with distinct biological activities, offering new avenues for treating various diseases and conditions.
Overall, 1-trifluoromethylcyclobutane-1-carboxylic acid is a versatile and valuable chemical entity in the fields of organic synthesis, pharmaceutical research, and drug discovery, owing to its unique structural features and the potential it holds for creating molecules with enhanced biological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 277756-45-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,7,7,7,5 and 6 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 277756-45:
(8*2)+(7*7)+(6*7)+(5*7)+(4*5)+(3*6)+(2*4)+(1*5)=193
193 % 10 = 3
So 277756-45-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H7F3O2/c7-6(8,9)5(4(10)11)2-1-3-5/h1-3H2,(H,10,11)
277756-45-3Relevant academic research and scientific papers
Selective reactions of 1,1-cycloalkanedicarboxylic acids with SF4. a route to 1,1-bis(trifluoromethyl)cycloalkanes, 1-fluoroformyl-1-(trifluoromethyl)cycloalkanes and 1-(trifluoromethyl)-1-cycloalkanecarboxylic acids
Dmowski, Wojciech,Wolniewicz, Adam
, p. 141 - 146 (2007/10/03)
Six-, five-, four- and three-membered 1,1-cycloalkanedicarboxylic acid (2a-d) were synthesized by alkaline hydrolysis of the corresponding diesters (1a-d) and the reactions of the formers with SF4 were investigated. 1,1-Bis(trifluoromethyl)cycloalkanes (3a-d) were the products of the reactions conducted at 120-150°C while at 30°C 1-fluoroformyl-1-(trifluoromethyl)cycloalkanes (4a-d) were exclusively formed. The latter were isolated as pure compounds or converted in situ into 1-(trifluoromethyl)-1-cycloalkanecarboxylic acids (5a-d).
