277757-85-4

Upstream product

• 103174-02-3 (3R,4S)-cis-1-(p-anisyl)-3-acetoxy-4-<(S)-2,2-dimethyl-1,3-dioxolan-4-yl>azetidin-2-one 
• 115828-87-0 (3R,4S)-cis-1-(p-anisyl)-3-hydroxy-4-<(S)-2,2-dimethyl-1,3-dioxolan-4-yl>azetidin-2-one 
• 103239-04-9 N-(p-anisyl)-4-<(S)-2',2'-dimethyl-1',3'-dioxolan-4'-yl>-methylene-imine 
• 277757-28-5 (+)-(3R,4S)-3-(2-carboxymethyl-1-ethenyloxy)-4-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-1-(p-methoxyphenyl)-2-azetidinone 

Downstream Products

• 277757-73-0 (+)-(3R,4R)-3-(2-carboxymethyl-1-ethenyloxy)-4-formyl-1-(p-methoxyphenyl)-2-azetidinone 

Relevant academic research and scientific papers

Stereoselective allylation of 4-oxoazetidine-2-carbaldehydes. Application to the stereocontrolled synthesis of fused tricyclic β-lactams via intramolecular Diels-Alder reaction of 2-azetidinone-tethered trienes

Allylation reactions of racemic and optically pure 4-oxoazetidine-2- carbaldehydes were investigated both under anhydrous conditions and in aqueous media. Different Lewis acid or metal mediators showed varied diastereoselectivities on product formation du