27792-82-1 Usage
Description
The EtOH extract of Urechites karwinskii roots contains this necine base. NaBH4 reduces the ketone group to a secondary hydroxyl while Mn02 oxidizes the
hydroxylmethyl group to the aldehyde.
References
Del Castillo et ai., Tetrahedron Lett., 1219 (1970)
Check Digit Verification of cas no
The CAS Registry Mumber 27792-82-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,7,9 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 27792-82:
(7*2)+(6*7)+(5*7)+(4*9)+(3*2)+(2*8)+(1*2)=151
151 % 10 = 1
So 27792-82-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO2/c10-5-6-1-3-9-4-2-7(11)8(6)9/h1,3,10H,2,4-5H2
27792-82-1Relevant articles and documents
Synthesis of 2,3-Dihydro-7-hydroxymethyl-1H-pyrrolizin-1-one, the Alkaloid Loroquine
Roeder, Erhard,Bartkowski, Jan-Pit Barko,Bourauel, Thomas
, p. 711 - 714 (2007/10/02)
The title compound 4 is synthesized in 8 steps by cyclization of N-tosylglycinate 5 with vinyl ketone 6.After elimination of water and sulfinic acid the pyrrolecarboxylate 9 is obtained which, on N-alkylation with ethyl acrylate, Dieckmann cyclization, saponification and decarboxylation, yields methylloroquine 12.The reaction with chlorotrimethylsilane/sulfuric acid in acetic anhydride and subsequent saponification gave loroquine (4) in 2.1 percent overall yiels.Key Words: Pheromones / Pyrrolizidine alkaloids / Pyrrolizine / Alkaloids