27806-85-5

Upstream product

• 104-94-9 4-methoxy-aniline 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 
• 2293-07-4 1-(4-methoxyphenyl)thiourea 
• 74-88-4 methyl iodide 
• 21258-08-2 N-(4-anisyl)-N'-benzoylthiourea 

Downstream Products

• 27806-78-6 N-(4-methoxy-phenyl)-S-methyl-isothiourea 
• 56204-42-3 N¹-(4-Methoxyphenyl)aminoguanidinhydroiodid 
• 117638-67-2 C₁₈H₁₇N₅O 
• 1269487-67-3 (4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(4-methoxyphenyl)amino]imidazoline hydrochloride 
• 1596354-70-9 N-(4-methoxyphenyl)-5-(6-fluoro-2-(4-fluorophenyl)quinolin-4-yl)-4H-1,2,4-triazol-3-amine 
• 119155-37-2 N-(4-Methoxy-phenyl)-pyrrolidine-1-carboxamidine; hydriodide 
• 65070-16-8 N-Cyclohexylmethyl-N'-(4-methoxy-phenyl)-guanidine 
• 1269603-77-1 (4S)-4-(N-benzyloxycarbonyl-2-aminoethyl)-2-[(4-methoxyphenyl)amino]imidazoline 
• 16518-84-6 (4-methoxy-phenyl)-selenourea 

Relevant academic research and scientific papers

Heterocyclic compounds useful for kinase inhibition

Provided herein are compounds useful for kinase inhibition.

New imidazoline/α2-adrenoceptors affecting compounds-4(5)-(2-aminoethyl)imidazoline (dihydrohistamine) derivatives. Synthesis and receptor affinity studies

Compilation of agmatine structure and imidazoline moiety leads to a new group of imidazoline/α2-adrenoceptor ligands, 4(5)-(2-aminoethyl)imidazoline derivatives. In this study the exploration of previously unknown 4(5)-(2-aminoethyl)imidazolines including the analogues of reported imidazoline and α2-aderenoceptors ligands: clonidine, rilmenidine, idazoxan, efaroxan, antazoline, tracizoline is described. The synthesis of a variety of novel 4(5)-(2-aminoethyl)imidazolines and their I 1, I2, α2-adrenoceptors affinities are reported.

Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors

A novel triazole-containing chemical series was shown to inhibit tubulin polymerization and cause cell cycle arrest in A431 cancer cells with EC 50 values in the single digit nanomolar range. Binding experiments demonstrated that representative

Flavin receptors. Effect of the acidity of melamine derivatives bearing a 2-arylguanidinium ion on 6-azaflavin binding in chloroform

The pK(a)'s of melamine derivatives beating a 2-arylguanidinium ion and their binding constants for 6-aza-10dodecylisoalloxazine (6-azaflavin) were nicely correlated with the Hammett o of the substituents. However, the rates of the oxidations of N-benzyl-

A Versatile Synthesis of Novel N,N,N''-Trisubstituted Guanidines

N,N,N''-Trisubstituted guanidines (most of them N''-aryl-N-azacycloalkanecarboximidamides) are prepared in generally good yields by S-methylation of monosubstituted thioureas with methyl iodide in methanol or acetone and reaction of the resultant methyl c

Zur Kinetik der Oxydation 3-substituierter 1-Aminoguanidine durch Cerium(IV) in perchlorsaurer Loesung. 1. Teil

By known manners synthesized 1-amino-3-aryl-guanidines are oxidatively cyclized to corresponding 3,6-diarylamino-1,2,4,5-tetrazines in perchloric acid solution.The kinetics of this passing with second order model reaction was studied on a selected series of 17 1-amino-3-aryl-guanidine hydronitrates at 4 temperatures in 4 differently concentrated perchloric acid solutions of constant ionic strength by photometric concentration determination of oxidant cerium(IV).From experimental data rate constants, activation parameters and catalytic constants are evaluated by conventional methods, tabulated and discussed with regard to their substituent dependence.