278170-35-7

Upstream product

• 109-92-2 ethyl vinyl ether 
• 278170-34-6 (2S)-1-(4-Fluorophenoxy)pent-4-en-2-ol 
• 104605-98-3 (2S)-2-[(4-fluorophenoxy)methyl]oxirane 

Downstream Products

• 278170-36-8 (2S)-2-(4-Fluorophenoxymethyl)-2,3-dihydrofuran 
• 175212-45-0 (2S,5S)-trans-5-(4-fluorophenoxymethyl)-5-(4-N,O-bis-(phenoxycarbonyl)hydroxylamino-3-butyn-4-yl)tetrahydrofuran 
• 253866-75-0 2-{4-[(S)-5-(4-Fluoro-phenoxymethyl)-tetrahydro-furan-2-yl]-but-3-ynyloxy}-tetrahydro-pyran 
• 278170-37-9 (2S,5S)-2-(Benzenesulfonyl)-5-(4-fluorophenoxymethyl)tetrahydrofuran 
• 220623-71-2 (2S,5S)-trans-5-((4-fluorophenoxy)methyl)-2-(1-hydroxy-3-butyn-4-yl)tetrahydrofuran 

Relevant academic research and scientific papers

A versatile approach to anti-asthmatic compound CMI-977 and its six- membered analogue

The synthesis of the anti-asthmatic compound CMI-977 is described. The tetrahydrofuran ring was effectively constructed by involving olefin metathesis while the stereoselective introduction of the 1-N- hydroxyureidylbut-3-yn-4-yl side-chain was achieved b