278172-08-0Relevant academic research and scientific papers
Controllable synthesis of 2- And 3-aryl-benzomorpholines from 2-aminophenols and 4-vinylphenols
Dong, Kui,Jin, Xiao-Ling,Chen, Shihao,Wu, Li-Zhu,Liu, Qiang
supporting information, p. 7941 - 7944 (2020/08/14)
We present herein a method for the controllable synthesis of 3-aryl-benzomorpholine and 2-aryl-benzomorpholine cycloadducts via cross-coupling/annulation between electron-rich 2-aminophenols and 4-vinylphenols. Molecular oxygen was successfully used in the reaction as the terminal oxidant and the complete inversion of chemoselectivity was achieved by the adjustment of the solvents and bases at room temperature.
Metal-free ortho C-H borylation of 2-phenoxypyridines under mild conditions
Niu, Liting,Yang, Haijun,Wang, Ruji,Fu, Hua
supporting information; experimental part, p. 2618 - 2621 (2012/07/14)
An efficient metal-free ortho C-H borylation has been developed via sequential borylation of substituted 2-phenoxypyridines with BBr3 following esterification with pinacol. The corresponding aryl boronates were obtained in good yields. The synt
Copper-catalyzed direct synthesis of di- and triphenylamines: A dramatic accelerating effect of 2-aminophenols
Li, Yaming,Wang, Huifeng,Jiang, Linlin,Sun, Fangfang,Fu, Xinmei,Duan, Chunying
experimental part, p. 6967 - 6973 (2011/02/25)
Utilizing the dramatic accelerating effect of 2-aminophenols, we developed a copper-catalyzed system for the selective synthesis of di- and triphenylamines. In addition, N- and O-arylation could be achieved in coupling reactions between 2-aminophenol and nitroaryl halides. A copper-catalyzed system for the selective synthesis of di- and triphenylamines has been developed. This new protocol provides a direct and efficient way to synthesize o-hydroxy-substituted di- and triphenylamines. Copyright
