278597-15-2Relevant articles and documents
Discovery and preliminary SAR of 5-arylidene-2,2-dimethyl-1,3-dioxane-4,6- diones as platelet aggregation inhibitors
El Maatougui, Abdelaziz,Azuaje, Jhonny,Coelho, Alberto,Yaziji, Vicente,Carbajales, Carlos,Sotelo, Eddy,Lopez, Carmen,Cano, Ernesto,Yanez, Matilde
, p. 551 - 554,4 (2020/08/31)
We herein document the discovery of 5-arylidene-2,2-dimethyl-1,3-dioxane-4, 6-diones as a novel family of platelet aggregation inhibitors. The preliminary optimization study enabled us to establish the most salient features of the structure-activity relat