27894-82-2Relevant articles and documents
Aryl O- and S-galactosides and lactosides as specific inhibitors of human galectins-1 and -3: Role of electrostatic potential at O-3
Giguere, Denis,Sato, Sachiko,St-Pierre, Christian,Sirois, Suzanne,Roy, Rene
, p. 1668 - 1672 (2007/10/03)
Phase transfer catalyzed reaction was used for the high yielding synthesis of aryl 1-thio-β-d-galacto- and lacto-pyranosides carrying a panel of substituents on the phenyl groups. Best galectin-1 inhibitors were simple p-nitrophenyl thiogalactoside 5a for
Synthesis of glycopolymers containing GM3-saccharide
Cao,Roy
, p. 3421 - 3434 (2007/10/03)
GM3-trisaccharide [Neu5Acα-)2 → 3)-Galβ-(1 → 4)-Glcβ-(1 → OR] was synthesized using our 'active-latent' thioglycosylation strategy. The trisaccharide was prepared with a p-acrylamidophenyl aglycon for copolymerization with acrylamide. The resulting water-soluble sialyl α-(2 → 3)-lactoside copolyacrylamide with different carbohydrate incorporation was shown to possess antigenic properties.