27894-82-2

Upstream product

• 3616-19-1 lactose octaacetate 
• 4753-07-5 2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide 
• 1849-36-1 para-nitrobenzenethiol 
• 27894-81-1 4-nitrophenyl 2,3,6,2',3',4',6'-hepta-O-acetyl-1-thio-β-lactoside 

Downstream Products

• 178425-73-5 4-nitrophenyl 3',4'-O-isopropylidene-1-thio-β-D-lactopyranoside 
• 1256485-13-8 C₄₀H₄₄N₂O₁₉S 
• 1256485-14-9 C₂₈H₃₂N₂O₁₃S 
• 178425-74-6 p-nitrophenyl 2,6,6'-tri-O-benzoyl-3',4'-O-isopropylidene-1-thio-β-D-lactoside 
• 178425-77-9 C₂₉H₄₂N₂O₂₀S 
• 178425-75-7 p-nitrophenyl 2,6,6'-tri-O-benzoyl-1-thio-β-D-lactoside 
• 178425-78-0 C₂₉H₄₄N₂O₁₈S 
• 178425-76-8 C₅₉H₆₄N₂O₂₇S 

Relevant academic research and scientific papers

Aryl O- and S-galactosides and lactosides as specific inhibitors of human galectins-1 and -3: Role of electrostatic potential at O-3

Phase transfer catalyzed reaction was used for the high yielding synthesis of aryl 1-thio-β-d-galacto- and lacto-pyranosides carrying a panel of substituents on the phenyl groups. Best galectin-1 inhibitors were simple p-nitrophenyl thiogalactoside 5a for

Synthesis of glycopolymers containing GM3-saccharide

GM3-trisaccharide [Neu5Acα-)2 → 3)-Galβ-(1 → 4)-Glcβ-(1 → OR] was synthesized using our 'active-latent' thioglycosylation strategy. The trisaccharide was prepared with a p-acrylamidophenyl aglycon for copolymerization with acrylamide. The resulting water-soluble sialyl α-(2 → 3)-lactoside copolyacrylamide with different carbohydrate incorporation was shown to possess antigenic properties.