2791-05-1 Usage
General Description
ACTH (1-10) is a synthetic peptide that comprises the first ten amino acids of the adrenocorticotropic hormone (ACTH). This hormone plays a crucial role in regulating the production and release of steroid hormones such as cortisol in the adrenal glands. ACTH (1-10) is often used in laboratory research to study the physiological effects and signaling pathways of the full-length ACTH hormone. It has also been investigated for its potential therapeutic applications in treating conditions such as adrenal insufficiency and related disorders. Additionally, ACTH (1-10) has been studied for its role in modulating the immune response and inflammation, making it a promising target for pharmaceutical development in the future.
Check Digit Verification of cas no
The CAS Registry Mumber 2791-05-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,7,9 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2791-05:
(6*2)+(5*7)+(4*9)+(3*1)+(2*0)+(1*5)=91
91 % 10 = 1
So 2791-05-1 is a valid CAS Registry Number.
InChI:InChI=1/C59H78N16O16S/c1-92-21-19-42(70-58(91)47(30-77)75-56(89)43(71-50(83)38(60)29-76)23-33-13-15-36(78)16-14-33)54(87)69-41(17-18-48(79)80)53(86)74-46(25-35-27-63-31-67-35)57(90)72-44(22-32-8-3-2-4-9-32)55(88)68-40(12-7-20-64-59(61)62)52(85)73-45(51(84)66-28-49(81)82)24-34-26-65-39-11-6-5-10-37(34)39/h2-6,8-11,13-16,26-27,31,38,40-47,65,76-78H,7,12,17-25,28-30,60H2,1H3,(H,63,67)(H,66,84)(H,68,88)(H,69,87)(H,70,91)(H,71,83)(H,72,90)(H,73,85)(H,74,86)(H,75,89)(H,79,80)(H,81,82)(H4,61,62,64)/t38-,40-,41-,42-,43-,44-,45-,46-,47-/m0/s1
2791-05-1Relevant articles and documents
MODIFICATION OF TRYPTOPHAN RESIDUES DURING ACIDOLYSIS OF 4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL GROUPS. EFFECTS OF SCAVENGERS
Sieber, Peter
, p. 1637 - 1640 (1987)
The formation of by-product 1 of tryptophan during the cleavage of Mtr from arginine can be minimized by addition of 1,2-ethanedithiol.Under too drastic conditions, however, a dithioketal product 2 is formed.
APPLICATION OF THE NG-(2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULPHONYL) DERIVATIVE OF FMOC-ARGININE TO PEPTIDE SYNTHESIS
Green, J.,Ogunjobi, O. M.,Ramage, R.,Stewart, A. S. J.
, p. 4341 - 4344 (2007/10/02)
The trifluoroacetic acid labile pentamethylchromanylsulphonyl protecting group for the guanidino group of arginine has been used in conjunction with the base-labile Fmoc Nα protecting group for the synthesis of arginine-containing peptides.
