27919-75-1

Upstream product

• 123-12-6 N,N,N',N'-tetraethyldiethylenetriamine 
• 459-57-4 4-fluorobenzaldehyde 
• 5427-46-3 N,N-bis-(2-diethylamino-ethyl)-aniline 
• 93-61-8 N-methyl-N-phenylformamide 

Relevant academic research and scientific papers

2-phenyl benzimidazole derivatives as MCP-1 antagonists

Benzimidazole derivatives of Formula I or a pharmaceutically acceptable salt thereof are MCP-1 antagonists and are thus useful in the treatment of inflammation, atherosclerosis, restenosis, and immune disorders wherein A is N or CH; where W, X, Y, and Z can be independently C—R2, C—R3, C—R4, C—R5, or N; no more than two of W, X, Y, and Z can be N in any one structure, R2, R3, R4, and R5are as define in the specification.

2-PHENYL BENZIMIDAZOLE DERIVATIVES AS MCP-1 ANTAGONISTS

The present invention relates to novel compounds and medical methods of treatment of inflammation, atherosclerosis, restenosis, and immune disorders especially those associated with lymphocyte or monocyte accumulation such as arthritis and transplant reje