279221-72-6

Upstream product

• 102487-47-8 (E,4S,5R,6R)-methyl 5,7-di(benzyloxy)-4,6-dihydroxy-2-heptenoate 
• 2033-24-1 cycl-isopropylidene malonate 
• 16054-77-6 3,5-di-O-benzyl-D-xylofuranose 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 1451180-66-7 C₂₂H₂₄O₄ 
• 1451180-67-8 C₂₅H₂₈O₆ 
• 1451180-69-0 C₂₅H₂₈O₇ 
• 1350649-50-1 3,6-anhydro-5-O-benzyl-2-deoxy-7-O-nonyl-D-ido-heptono-1,4-lactone 

Relevant academic research and scientific papers

Synthesis and antiproliferative activity of simplified goniofufurone analogues

Several (+)-goniofufurone analogues with simplified structures were designed, synthesized and evaluated for their in vitro antitumour activity, against a panel of human tumour cell lines. Dephenylated compounds 2 and 3 demonstrated remarkable antitumour a

Heteroannelated (+)-muricatacin mimics: Synthesis, antiproliferative properties and structure-activity relationships

Six new (+)-muricatacin mimics bearing a furano-furanone core have been synthesized and their in vitro antiproliferative activity was evaluated against a panel of human tumour cell lines. A straightforward total synthesis of (+)-muricatacin (1) from d-xyl

Wittig reaction with partially protected sugar lactol derivatives. Preparation of highly cytotoxic goniofufurone analogues

A new approach to the dephenyl goniofufurone analogue 2 and the corresponding (3S,4R)-stereoisomer 3 is reported. The resulting furanolactones 2 and 3 have shown a potent and selective in vitro cytotoxicity against certain human tumour cell lines.