27955-58-4Relevant articles and documents
Synthesis, structural characterization and antioxidative properties of aminopyrazine and imidazolopyrazine derivatives
Devillers, Ingrid,De Wergifosse, Bertrand,Bruneau, Marie-Pierre,Tinant, Bernard,Declercq, Jean-Paul,Touillaux, Roland,Rees, Jean-Francois,Marchand-Brynaert, Jacqueline
, p. 1481 - 1487 (2007/10/03)
The reaction of 2-aminopyrazine 1 with the glyoxal derivatives 2a-c gave the bicyclic imidazolopyrazinones 3a,b and the monocyclic N-substituted aminopyrazines 4b and 5c. Compounds 3 feature unique crystallographic characteristics. Their reactivity towards superoxide anion is about five times the reactivity of Trolox , while the monocyclic pyrazines are inactive.
Imidazopyridazines and an Imidazopyrazine from Pyridazin- and Pyrazin-amines
Barlin, Gordon B.,Brown, Desmond J.,Kadunc, Zdenka,Petric, Andrej,Stanovnik, Branko,Tisler, Miha
, p. 1215 - 1220 (2007/10/02)
The ambiguous condensations of phenylglyoxal with pyridazin-3-amines and pyrazin-2-amine are shown to yield 2-phenylimidazopyridazin-3(5H)-ones and imidazopyrazin-3(7H)-one, respectively.The former products exist as such, at least in the solid state, whereas the latter product exists to a large extent as the corresponding dipolar molecule.The reactions, degradations and n.m.r. spectra of the products are discussed.