27964-07-4 Usage
General Description
2-amino-1-methyl-9-pentofuranosyl-7,9-dihydro-1H-purine-6,8-dione is an organic compound that belongs to the family of purines. It is a derivative of the nucleoside adenosine and is an important component of DNA and RNA. This chemical is commonly known as Adenine, one of the four nucleobases that make up the genetic code in DNA and RNA. Adenine plays a crucial role in storing and transferring genetic information in living organisms. It is also involved in various biological processes, such as energy metabolism and signal transduction. Furthermore, Adenine is an essential component of many coenzymes, such as NAD and FAD, which are involved in various metabolic pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 27964-07-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,9,6 and 4 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 27964-07:
(7*2)+(6*7)+(5*9)+(4*6)+(3*4)+(2*0)+(1*7)=144
144 % 10 = 4
So 27964-07-4 is a valid CAS Registry Number.
27964-07-4Relevant academic research and scientific papers
ELECTROPHILIC AMINATION OF GUANINE DERIVATIVES. MECHANISM FOR FORMATION OF 8-AMINOGUANINE DERIVATIVES
Kohda, Kohfuku,Baba, Kunihisa,Kawazoe, Yutaka
, p. 1531 - 1540 (2007/10/02)
A study of the mechanism of 8-aminoguanosine formation in the reaction of guanosine with hydroxylamine-O-sulfonic acid (HAOS) revealed that the reaction proceeds in three steps; 1) electrophilic N-7 amination by HAOS, 2) nucleophilic C-8 hydroxyamination by NH2OH accompanied by elimination of the N-7 amino group and by aromatization, and finally 3) the reduction of the C-8 hydroxyamino group by NH2OH to give 8-aminoguanosine.The significance of formation of the 7-aminoguanosine intermediate is discussed briefly in relation to thr reaction of carcinogenic arylamines and arylhydroxylamines with cellular DNA.
