27976-83-6Relevant academic research and scientific papers
Compound, preparation method thereof and application of compound as fluorescent probe
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Paragraph 0117-0118; 0123, (2021/11/10)
The invention discloses a compound, a preparation method thereof and application of the compound as a fluorescent probe, wherein the compound I is selected from at least one compound of the chemical formula shown I. I In formula R1 . R2 Independently selected C1 - C5 Alkyl, C1 - C5 Alkoxy and substituted C1 - C5 At least one of the alkyl I of the alkyl group. R3 Be selected from C1 - C5 Alkyl groups. Substituted C1 - C5 At least one of the alkyl II groups of the alkyl group. The fluorescence probe provided by the invention can detect the morphology and the position of protein aggregation states through fluorescent imaging in living cells.
Cobalt-Catalyzed α-Arylation of Substituted α-Halogeno β-Lactams
Koch, Vanessa,Lorion, Mélanie M.,Barde, Etienne,Br?se, Stefan,Cossy, Janine
supporting information, p. 6241 - 6244 (2019/08/26)
The treatment of 3-bromo β-lactams by an aryl Grignard, in the presence of CoCl2 (2 mol %) and TMEDA (2 mol %) in THF, produces 3-aryl β-lactams in good yields and excellent diastereoselectivity.
Efficient synthesis of new 4-arylideneimidazolin-5-ones related to the GFP chromophore by 2+3 cyclocondensation of arylideneimines with imidate ylides
Baldridge, Anthony,Kowalik, Janusz,Tolbert, Laren M.
scheme or table, p. 2424 - 2436 (2010/09/06)
A 2+3 condensation of a wide assortment of Schiff bases, prepared from aromatic aldehydes and primary amines, with methyl (1-ethoxyethylideneamino) acetate allows convenient access to an extensive family of substituted 4-arylideneimidazolin-5-one analogues of the green fluorescent protein (GFP) chromophore. Georg Thieme Verlag Stuttgart · New York.
Kinetics and mechanism of the Pudovik reaction in the azomethine series: I. Addition of dimethyl hydrogen phosphite to N-isopropylbenzalimines
Sobanov,Zolotukhin,Galkin,Cherkasov,Pudovik
, p. 1067 - 1070 (2007/10/03)
For a series of phenyl-substituted N-isopropylbenzalimines, the effect of substituent on their capability to add dimethyl hydrogen phosphite was studied qualitatively in the condensed phase (DTA) and quantitatively (with determination of the kinetic and activation parameters) in 2-propanol solutions with spectrophotometric monitoring of the reaction. A reaction mechanism was proposed, involving formation of a highly organized four-membered transition state.
