27994-76-9Relevant academic research and scientific papers
Mechanisms of Bromination of Uracil Derivatives. 5. Reaction of Uracil and 5-Bromouracil via Their Anions in Weakly Acidic Aqueous Solution
Tee, Oswald S.,Berks, Charles G.
, p. 830 - 835 (1980)
The rates of reaction of bromine with uracil, 1-methyluracil, 3-methyluracil, 1,3-dimethyluracil, 5-bromouracil, and 5-bromo-1,3-dimethyluracil have been measured in acidic, aqueous solutions (pH 0-5).For those derivatives having a methyl group at N1 the observed second-order rate constants are invariant with acidity, whereas for those derivatives having hydrogen at N1 they increase with decreasing acidity.These results suggest that reaction upon the anions of uracil, 3-methyluracil, and 5-bromouracil predominates at higher pH.The mechanistic implications of these findings are discussed.
Oxidation of 5-Bromo- and 5-Fluoro-1,3-dimethyluracils by Peroxomono- and Peroxodisulfate Ions
Itahara, Toshio,Nishino, Akihiro
, p. 2203 - 2204 (2007/10/02)
Oxidation of 5-bromo-1,3-dimethyluracil by KHSO5 gave 5,5-dibromo-6-hydroxy- and 5,5,6-trihydroxy-1,3-dimethyl-5,6-dihydrouracils and that of 5-fluoro-1,3-dimethyluracil by Na2S2O8 gave a 6,6'-dimeric product.
