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Glycine chloramphenicol ester hydrochloride is a chemical compound derived from chloramphenicol, an antibiotic used to treat a variety of bacterial infections. This specific ester is formed by the reaction of chloramphenicol with glycine, a simple amino acid, and hydrochloric acid. The resulting compound serves as a prodrug, meaning it is inactive in its current form and must be metabolized in the body to release the active chloramphenicol. This modification can improve the drug's pharmacokinetic properties, such as absorption, distribution, and elimination, potentially enhancing its therapeutic efficacy and reducing side effects. The ester hydrochloride form also aids in stabilizing the compound and facilitating its dissolution in aqueous environments, which is crucial for its administration and absorption in medical applications.

2801-69-6

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2801-69-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2801-69-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,8,0 and 1 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2801-69:
(6*2)+(5*8)+(4*0)+(3*1)+(2*6)+(1*9)=76
76 % 10 = 6
So 2801-69-6 is a valid CAS Registry Number.

2801-69-6Downstream Products

2801-69-6Relevant academic research and scientific papers

In vitro RELEASE OF CHLORAMPHENICOL FROM POLY CARRIERS BY CATHEPSIN B

Ulbrich, Karel,Nazarova, Olga,Panarin, Eugenii,Baudys, Miroslav,Solovskii, Michail V.

, p. 1078 - 1085 (2007/10/02)

It has been shown in recent years that copolymers of N-(2-hydroxypropyl)methacrylamide may be used as targeted polymer drug carriers.The wide-spectrum antibiotic chloramphenicol has been bound to these carriers by means of biodegradable oligopeptide seque

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