280111-51-5

Basic information

• Product Name: 4-Hydrazino-piperidine-1-carboxylic acid benzyl ester
• Synonyms: 4-Hydrazino-piperidine-1-carboxylic acid benzyl ester;benzyl 4-hydrazinylpiperidine-1-carboxylate
• CAS NO: 280111-51-5
• Molecular Formula: C₁₃H₁₉N₃O₂
• Molecular Weight: 249.30886
• Mol File: 280111-51-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Hydrazino-piperidine-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydrazino-piperidine-1-carboxylic acid benzyl ester(280111-51-5)
• EPA Substance Registry System: 4-Hydrazino-piperidine-1-carboxylic acid benzyl ester(280111-51-5)

Safety Data

• Hazardous Substances Data: 280111-51-5(Hazardous Substances Data)

Upstream product

• 280111-50-4 benzyl 4-(2-(tert-butoxycarbonyl)hydrazinyl)piperidine-1-carboxylate 
• 19099-93-5 benzyl 4-oxo-1-piperidinecarboxylate 

Downstream Products

• 1443248-23-4 4-[3-tert-butyl-5-(2,2,2-trichloro-ethoxycarbonylamino)-pyrazol-1-yl]-piperidine-1-carboxylic acid benzyl ester 
• 1443248-25-6 4-(3-tert-butyl-5-{3-[(1S,4R)-4-(3-isopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-ureido}-pyrazol-1-yl)-piperidine-1-carboxylic acid benzyl ester 
• 1443248-20-1 4-(5-amino-3-tert-butyl-pyrazol-1-yl)-piperidine-1-carboxylic acid benzyl ester 
• 1211548-02-5 4-[5-(4-methoxy-phenyl)-3-methyl-[1,2,4]triazol-1-yl]-piperidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) MODULATORS AND USES THEREOF

Provided herein are small molecule modulators of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.

KINASE INHIBITORS

Compounds of formula (I): wherein R2, W, A, Y, and R1 are as defined in the specification, and pharmaceutically acceptable salts thereof, are p38 MAPK inhibitors, and are useful as anti-inflammatory agents in the treatment of, inter alia, diseases of the respiratory tract.

SMALL MOLECULE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASES (PRMTS)

The present invention relates to compounds that are useful as inhibitors of protein arginine methyltransferase that have a formula selected from Formula (I), Formula (II) and Formula (III), as well as racemic mixtures, diastereomers, enantiomers and tautomers thereof and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof as defined herein. Said compound are useful as inhibitors of PRMTs and/or CARM-I. The invention further relates to compositions comprising such compounds and methods for their use.