280123-47-9Relevant academic research and scientific papers
REMEDIES FOR PAIN
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, (2008/06/13)
The present invention provides a pain control agent, which contains, as an active ingredient, a compound having both μ opioid receptor agonist activity and dopamine D2 receptor antagonist activity. The compound having both of these activities exerts a potent morphine-like analgetic effect and causes no psychological dependence, and even regulates side effects. In particular, a novel compound represented by general formula (I) or a pharmacologically acceptable salt thereof has both μ opioid receptor agonist activity and dopamine D2 receptor antagonist activity, and is useful as pain control agent with regulated side effects.
