280141-67-5

Basic information

• Product Name: C₂₇H₃₆N₄O₆
• Synonyms: C₂₇H₃₆N₄O₆
• CAS NO: 280141-67-5
• Molecular Weight: 512.606
• Mol File: 280141-67-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₆N₄O₆(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₆N₄O₆(280141-67-5)
• EPA Substance Registry System: C₂₇H₃₆N₄O₆(280141-67-5)

Safety Data

• Hazardous Substances Data: 280141-67-5(Hazardous Substances Data)

Upstream product

• 280141-66-4 C₂₂H₂₅N₃O₅ 
• 15028-41-8 methyl 2-aminoisobutyrate hydrochloride 

Downstream Products

• 280141-79-9 C₂₁H₃₁N₃O₃ 

Relevant articles and documents

SUBSTITUTED OXIMES AND HYDRAZONES AS NEUROKININ ANTAGONISTS

Compound represented by structural formula (I) or a pharmaceutical acceptable salt thereof, wherein a is 0-3; b, d and e are 0-2; R is H, alkyl, F or -OR; A is an optionally substituted oxime or hydrazone; d is not 0 and X is a bond, -C(O)-, -O-, -NR-, -S(O)e-, -N(R)C(O)-, -C(O)N(R)-, -OC(O)NR-, -OC(=S)NR-, -N(R)C(=S)O-, -S(O)2N(R)-, -N(R)S(O)2-, -N(R)C(O)O-, -OC(O)- or -N(R)C(O)NR-; or d is 0 and X is a bond or -NR-; T is H, aryl, heterocycloalkyl or heteroaryl; Q is phenyl, napthyl or heteroaryl; R is H, alkyl, hydroxyalkyl, alkoxyalkyl, phenyl, and benzyl; R is R or -OR, R, R, R and R are H or alkyl; Z is a nitrogen-containing heterocyclo group, e.g., piperidinyl, substituted by a heterocyclo- or heterocycloalkyl group; wherein phenyl, benzyl, aryl, heterocycloalkyl, heteroaryl and cycloalkyl groups are optionally substituted; methods of treating diseases such as asthma, cough, bronchospasm, depression, emesis, inflammatory diseases, and gastrointestinal disorders with said compounds, and pharmaceutical compositions comprising said compounds are disclosed.