28027-52-3 Usage
Nitrogen-containing heterocyclic compound
5-nitroindole This indicates that the compound is derived from 5-nitroindole, which is a nitrogen-containing heterocyclic compound.
Amine derivative
The presence of an amine group (-NH2) in the molecule This indicates that the compound is an amine derivative of 5-nitroindole.
Potentially reactive
Presence of a nitro group The presence of a nitro group (-NO2) in the molecule makes it potentially reactive, which may be important for its potential applications.
Precursors for the synthesis of biologically active molecules
Often used in research and pharmaceutical development This indicates that the compound is often used as a precursor for the synthesis of various biologically active molecules.
Valuable for the development of new drugs and therapeutic agents
Specific structure The specific structure of the compound may make it valuable for the development of new drugs and therapeutic agents.
Further studies and testing may reveal potential applications and effects on biological systems
The potential applications and effects of the compound on biological systems are not yet fully understood and require further studies and testing.
Check Digit Verification of cas no
The CAS Registry Mumber 28027-52-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,2 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 28027-52:
(7*2)+(6*8)+(5*0)+(4*2)+(3*7)+(2*5)+(1*2)=103
103 % 10 = 3
So 28027-52-3 is a valid CAS Registry Number.
28027-52-3Relevant academic research and scientific papers
Method for reducing intraocular pressure using indole derivatives
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, (2008/06/13)
The present invention provides a method of reducing intraocular pressure by administering pharmaceutical compositions comprising indole derivatives. The pharmaceutical compositions useful in this invention comprise indole derivatives and melatonin analogs of Formulae I-IV. A preferred embodiment is a method of lowering intraocular pressure using 5-(methoxycarbonylamino)-N-acetyltryptamine (5-MCA-NAT), also known as GR 135531, which has a prolonged duration of action and greater efficacy in lowering intraocular pressure compared to melatonin. The present invention further provides a method of treating disorders associated with ocular hypertension, and a method of treating various forms of glaucoma; the method comprises administering an effective dose of a pharmacuetical composition comprising an indole derivative with or without agents commonly used to treat such disorders.
