28030-93-5Relevant academic research and scientific papers
Syntheses of polyalkylated imidazoles
Evjen, Sigvart,Fiksdahl, Anne
supporting information, p. 1392 - 1399 (2017/07/25)
We have developed improved general simple methods for large-scale preparation of polyalkylated imidazoles by improved multicomponent synthesis from commercially available starting materials. A large range of NH- and N-alkyl-polyalkylimidazoles (40 in total, including novel compounds) has been synthesized.
Cross-coupling of phenyl halides with sodium dicyanomethanide in the presence of Tetrakis(triphenyphosphine)palladium
Wang, Jin,Shu, Cheng,Gao, Chao,Hou, Chaoqi,Peng, Bo,Wei, Wei
experimental part, p. 1325 - 1327 (2012/08/07)
1-Aromatic substituted imidazoles were synthesized by a convenient modified process. A cross-coupling reaction of phenyl halides with sodium dicyanomethanide has been achieved to produce the arylmalononitriles coupling products as zwitterionic precursors
Remarkable improvement achieved by imidazole derivatives in ruthenium-catalyzed hydroesterification of alkenes using formates
Konishi, Hideyuki,Muto, Takashi,Manabe, Kei,Ueda, Tsuyoshi
supporting information, p. 4722 - 4725,4 (2012/12/12)
Imidazole derivatives are revealed to be effective ligands in the Ru-catalyzed hydroesterification of alkenes using formates, affording one-carbonelongated esters in high yields. Further, intramolecular hydroesterification was successfully performed to give lactones for the first time. Imidazole derivatives can contribute to promote the reaction as well as to suppress the undesired decarbonylation of formate. Toxic CO gas, a directing group, and large excess alkenes are not required.
