Basic information

Product Name: Methyl 3-aMino-2,6-dichloroisonicotinate
Synonyms: methyl 3-amino-2,6-dibromoisonicotinate
CAS NO:28033-01-4
Molecular Formula: C7H6Cl2N2O2
Molecular Weight: 221.04074
EINECS: N/A
Product Categories: N/A
Mol File: 28033-01-4.mol

Chemical Properties

Melting Point: N/A
Boiling Point: 362.4±37.0 °C(Predicted)
Flash Point: N/A
Appearance: /
Density: 1.997±0.06 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
PKA: -2.18±0.10(Predicted)
CAS DataBase Reference: Methyl 3-aMino-2,6-dichloroisonicotinate(CAS DataBase Reference)
NIST Chemistry Reference: Methyl 3-aMino-2,6-dichloroisonicotinate(28033-01-4)
EPA Substance Registry System: Methyl 3-aMino-2,6-dichloroisonicotinate(28033-01-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 28033-01-4(Hazardous Substances Data)

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Usage
SDS
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28033-01-4 Usage

Uses

Used in Pharmaceutical Industry:
Methyl 3-aMino-2,6-dichloroisonicotinate is used as a synthetic intermediate for the development of carbazole and indolopyridine derivatives. These derivatives have been identified as potent Jak2 tyrosine kinase inhibitors, which play a crucial role in the treatment of various diseases, including cancer and autoimmune disorders. Methyl 3-aMino-2,6-dichloroisonicotinate's unique structure allows for the creation of targeted therapies that can effectively inhibit the activity of Jak2 tyrosine kinase, thereby disrupting the signaling pathways involved in disease progression.

Check Digit Verification of cas no

The CAS Registry Mumber 28033-01-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,3 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 28033-01:
(7*2)+(6*8)+(5*0)+(4*3)+(3*3)+(2*0)+(1*1)=84
84 % 10 = 4
So 28033-01-4 is a valid CAS Registry Number.

28033-01-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	3-amino-2,6-dibromo-isonicotinic acid methyl ester

1.2 Other means of identification

Product number	-
Other names	3-Amino-2,6-dibromo-isonicotinic acid methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:28033-01-4 SDS

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28033-01-4Downstream Products

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