28033-03-6 Usage
Uses
Used in Pharmaceutical Research:
Methyl 2-amino-5-nitroisonicotinate is used as a key intermediate in the development of antituberculosis drugs, contributing to the advancement of treatments for tuberculosis.
Used in Organic Synthesis:
Methyl 2-aMino-5-nitroisonicotinate is employed as a versatile building block in organic synthesis, enabling the creation of a range of biologically active molecules for various applications.
Used in Anticancer Research:
Methyl 2-amino-5-nitroisonicotinate is investigated for its potential anticancer properties, exploring its ability to target and inhibit the growth of cancer cells.
Used in Antimicrobial Research:
Methyl 2-aMino-5-nitroisonicotinate is also being studied for its antimicrobial properties, with potential applications in the development of new antibiotics to combat resistant bacterial strains.
Used in Medicinal Chemistry:
Methyl 2-amino-5-nitroisonicotinate holds promise in medicinal chemistry due to its potential to be incorporated into novel therapeutic agents targeting a variety of diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 28033-03-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,3 and 3 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 28033-03:
(7*2)+(6*8)+(5*0)+(4*3)+(3*3)+(2*0)+(1*3)=86
86 % 10 = 6
So 28033-03-6 is a valid CAS Registry Number.
28033-03-6Relevant articles and documents
Selective vicarious nucleophilic amination of 3-nitropyridines
Bakke, Jan M.,Svensen, Harald,Trevisan, Raffaela
, p. 376 - 378 (2007/10/03)
Nine 3-nitropyridine compounds and 4-nitroisoquinoline have been aminated in the 6-position (for 4-nitroisoquinoline in the 1-position) by vicarious nucleophilic substitution reactions. Two amination reagents were used, hydroxylamine and 4-amino-1,2,4-triazole. The yields were from moderate to good. Use of hydroxylamine gave an easy work-up procedure by which almost pure product was obtained directly, but 4-amino-1,2,4-triazole gave better yields of the aminated product for some of the substrates. By this, a general method for the preparation of 3- or 4-substituted-2-amino-5-nitropyridines was obtained.
