28035-02-1

Upstream product

• 541-47-9 3-Methylbutenoic acid 
• 108-98-5 thiophenol 

Downstream Products

• 1072933-01-7 (2,2-dimethyl-2H-thiochromen-4-yl)(phenyl)methanol 
• 1160309-79-4 (3,4-dimethoxyphenyl)(2,2-dimethyl-2H-thiochromen-4-yl)methanol 
• 1160309-85-2 (1-benzyl-1H-indol-2-yl)(2,2-dimethyl-2H-thiochromen-4-yl)methanol 
• 1314684-01-9 (1-benzyl-1H-indol-3-yl)(2,2-dimethyl-2H-thiochromen-4-yl)methanol 
• 1270009-53-4 N-[3,4-dihydro-4-(hydroxymethyl)-2,2,4-trimethyl-2H-1-benzothiopyran-6-yl]-N'-(4-nitrophenyl)thiourea 
• 1270009-64-7 N-[3,4-dihydro-4-(acetoxymethyl)-2,2,4-trimethyl-2H-1-benzothiopyran-6-yl]-N'-(4-nitrophenyl)thiourea 
• 78073-20-8 2-(3-methylcrotonoyl)-N-(p-tolylsulphonyl)benzenesulphenamide 
• 3844-31-3 trans-thioindigo 
• 77820-75-8 dimethyl (2-β-methylcrotonoylphenyl)thiomalonate 
• 5789-28-6 thioindirubin 
• 81576-32-1 6,6-dimethyl-6H-bis<1>benzothieno<3,2-b;3',2'-d>pyran 
• 13189-17-8 2,2-dimethyl-4-oxothiochroman S-oxide 
• 78073-19-5 2,2-dimethyl-1-(p-tolylsulphonylimino)thiochroman-4-one 

Relevant academic research and scientific papers

Direct aromatic tert-butylation during the synthesis of thiochroman-4-ones

The synthesis of thiochroman-4-ones from thiophenols and 3-methylbut-2-enoic acid effected by methane sulphonic acid is accompanied by tert-butylation of the aromatic ring. 3-Arylthiobutanoic acids, available using β-butyrolactone, are efficiently cyclised in the same manner.