28049-62-9 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-Bromophenyl)-cyclobutanecarbonitrile is utilized as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(2-Bromophenyl)-cyclobutanecarbonitrile serves as a crucial component in the production of pesticides and other crop protection agents. Its incorporation enhances the effectiveness of these products, supporting agricultural productivity and crop protection.
Used in Fine Chemicals Industry:
1-(2-Bromophenyl)-cyclobutanecarbonitrile is employed as a building block in the synthesis of fine chemicals, which are high-purity chemicals used in various applications such as fragrances, dyes, and specialty chemicals. Its versatility in synthesis contributes to the creation of high-quality products in this industry.
Used in Drug Discovery and Development:
Due to its demonstrated biological activity, 1-(2-Bromophenyl)-cyclobutanecarbonitrile is used as a starting material in drug discovery and development. Its potential to interact with biological targets makes it a valuable compound in the search for new therapeutic agents and treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 28049-62-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,0,4 and 9 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 28049-62:
(7*2)+(6*8)+(5*0)+(4*4)+(3*9)+(2*6)+(1*2)=119
119 % 10 = 9
So 28049-62-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H10BrN/c12-10-5-2-1-4-9(10)11(8-13)6-3-7-11/h1-2,4-5H,3,6-7H2
28049-62-9Relevant academic research and scientific papers
Identification of A Novel Small-Molecule Binding Site of the Fat Mass and Obesity Associated Protein (FTO)
He, Wu,Zhou, Bin,Liu, Weijia,Zhang, Meizi,Shen, Zhenhua,Han, Zhifu,Jiang, Qingwei,Yang, Qinghua,Song, Chuanjun,Wang, Ruiyong,Niu, Tianhui,Han, Shengna,Zhang, Lirong,Wu, Jie,Guo, Feima,Zhao, Renbin,Yu, Wenquan,Chai, Jijie,Chang, Junbiao
, p. 7341 - 7348 (2015/10/05)
N-(5-Chloro-2,4-dihydroxyphenyl)-1-phenylcyclobutanecarboxamide (N-CDPCB, 1a) is found to be an inhibitor of the fat mass and obesity associated protein (FTO). The crystal structure of human FTO with 1a reveals a novel binding site for the FTO inhibitor and defines the molecular basis for recognition by FTO of the inhibitor. The identification of the new binding site offers new opportunities for further development of selective and potent inhibitors of FTO, which is expected to provide information concerning novel therapeutic targets for treatment of obesity or obesity-associated diseases.
Arylcycloalkane carboxylic esters, their use, pharmaceutical compositions and preparation
-
, (2008/06/13)
PCT No. PCT/SE97/01310 Sec. 371 Date Apr. 12, 1999 Sec. 102(e) Date Apr. 12, 1999 PCT Filed Jul. 23, 1997 PCT Pub. No. WO98/04517 PCT Pub. Date Feb. 5, 1998This invention relates to the use of 2-(diisopropylamino)-ethyl-1-phenyl-cyclopentane-carboxylate or 2-(diisopropylamino)-ethyl-1-phenyl-cyclohexane-carboxylate, or a pharmaceutically accceptable salt thereof, for treatment of urinary incontinence or irritable bowel syndrome (IBS).
