280571-46-2

Basic information

• Product Name: 4-[5-(4-fluorobenzyl)furan-2-yl]-2-hydroxy-4-oxobut-2-enoic acid
• CAS NO: 280571-46-2
• Molecular Formula: C₁₅H₁₁FO₅
• Molecular Weight: 290.2432
• Mol File: 280571-46-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 475.8°C at 760 mmHg
• Flash Point: 241.5°C
• Density: 1.409g/cm³
• Vapor Pressure: 7.36E-10mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: 4-[5-(4-fluorobenzyl)furan-2-yl]-2-hydroxy-4-oxobut-2-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5-(4-fluorobenzyl)furan-2-yl]-2-hydroxy-4-oxobut-2-enoic acid(280571-46-2)
• EPA Substance Registry System: 4-[5-(4-fluorobenzyl)furan-2-yl]-2-hydroxy-4-oxobut-2-enoic acid(280571-46-2)

Safety Data

• Hazardous Substances Data: 280571-46-2(Hazardous Substances Data)

Relevant articles and documents

Aromatic heterocycle compounds having HIV integrase inhibiting activities

A compound of the formula (I): wherein X is hydroxy, protected hydroxy or optionally substituted amino; Y is —COORAwherein RAis hydrogen or ester residue, —CONRBRCwherein RBand RCeach is independently hydrogen or amide residue, optionally substituted aryl or optionally substituted heteroaryl; and A1is optionally substituted heteroaryl; provided that a compound wherein Y and/or A1is optionally substituted indol-3-yl is excluded, a tautomer, a prodrug, a pharmaceutically acceptable salt or a hydrate thereof has an inhibitory activity against an integrase.