280574-98-3 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 8 carbon (C), 5 hydrogen (H), 2 fluorine (F), 3 nitrogen (N), and 1 oxygen (O) atoms.
Explanation
The compound has a benzene ring (a six-membered ring with alternating single and double bonds) fused to an isoxazole ring (a five-membered ring with two oxygen atoms and one nitrogen atom).
Explanation
The compound contains an amine group (-NH2) attached to the isoxazole ring, which is a basic functional group with a nitrogen atom bonded to two hydrogen atoms.
Explanation
The compound has two fluorine atoms (F) attached at the 5th and 6th positions of the isoxazole ring, which can influence the compound's reactivity, stability, and biological activity.
Explanation
The compound is a derivative of benzisoxazole, which is a heterocyclic aromatic compound containing both carbon and heteroatoms (oxygen and nitrogen) in its ring structure.
Explanation
Due to its unique structure and properties, 1,2-Benzisoxazol-3-amine,5,6-difluoro-(9CI) may have potential uses in the development of new drugs and pesticides.
Explanation
Additional research is needed to fully understand the compound's potential applications, biological activities, and any possible side effects or limitations.
Structure
Benzene ring fused to an isoxazole ring
Amino group
-NH2
Fluorine substitution
5,6-difluoro
Heterocyclic aromatic compound
Benzisoxazole derivative
Potential applications
Pharmaceutical and agrochemical industries
Further research
Exploration of potential uses and biological activities
Check Digit Verification of cas no
The CAS Registry Mumber 280574-98-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,8,0,5,7 and 4 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 280574-98:
(8*2)+(7*8)+(6*0)+(5*5)+(4*7)+(3*4)+(2*9)+(1*8)=163
163 % 10 = 3
So 280574-98-3 is a valid CAS Registry Number.
280574-98-3Relevant academic research and scientific papers
Lepore, Salvatore D.,Wiley, Michael R.
, p. 2924 - 2932 (2000)
Further exploration of the scope of our solid-phase method for the synthesis of 3-aminobenzisoxazoles (using the Kaiser oxime resin 1) is described. The effects of base, leaving group, and solvent on the nucleophilic aromatic substitution based resin-loading reaction are discussed. Representative aryloxime intermediates were subjected to a variety of acidic conditions commonly used in protecting group removal to establish the acid stability profile of this linker. Regioselectivity was evaluated with various di- and trifluorobenzonitriles, which gave single benzisoxazole products after loading and cyclorelease reactions. Substituent effects observed in the course of the acid stability and regioselectivity studies suggest that the nitrile plays a critical role in the oxime hydrolysis mechanism. Finally, to establish the compatibility of the aryloxime linker with a variety of useful on-resin synthetic transformations, functionalized substrates were loaded onto resin 1, and carbon-nitrogen, carbon-oxygen, and carbon-carbon bond-forming reactions were successfully executed.
