280583-02-0

Basic information

• Product Name: 1-(2-chloro-4-morpholinobenzyl)-2-methyl-6-((4-methylbenzene)sulfonylcarbamoyl)benzimidazole
• CAS NO: 280583-02-0
• Molecular Weight: 539.055
• Mol File: 280583-02-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-chloro-4-morpholinobenzyl)-2-methyl-6-((4-methylbenzene)sulfonylcarbamoyl)benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chloro-4-morpholinobenzyl)-2-methyl-6-((4-methylbenzene)sulfonylcarbamoyl)benzimidazole(280583-02-0)
• EPA Substance Registry System: 1-(2-chloro-4-morpholinobenzyl)-2-methyl-6-((4-methylbenzene)sulfonylcarbamoyl)benzimidazole(280583-02-0)

Safety Data

• Hazardous Substances Data: 280583-02-0(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 52409-22-0 tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ 
• 219571-41-2 1-(4-bromo-2-chlorobenzyl)-2-methyl-6-((4-methyl-benzene)sulfonylcarbamoyl)benzimidazole 
• 1184-88-9 sodium pivalate 
• 76144-87-1 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES

The present invention provides novel benzimidazole derivatives of the following formula (I) and salts thereof: wherein R1 represents a lower alkyl group or a lower alkyloxy-lower alkyl group: R2 represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 8 carbon atoms, an aryl group, and such; R3 represents a lower alkyl group, a lower alkenyl group, an aryl group, a lower alkylaryl group, an aryl-lower alkenyl group, a halothienyl group, a lower alkylamino group, or an aryl-lower alkylamino group; A represents a benzene ring, a naphthalene ring, or a pyridine ring; and X represents a halogen atom. The derivatives and their salts have blood sugar level-depressing activity or PDE5-inhibiting activity, and are useful as pharmaceutical preparations.