28072-10-8Relevant academic research and scientific papers
The Synthetic Potential of the Isocyanide-Cyanide Rearrangement
Meier, Michael,Ruechardt, Christoph
, p. 1 - 4 (2007/10/02)
Excellent chemical and optical yields (>96percent retention) of cyanides are achieved by vapor phase thermolysis or short contact flow thermolysis of isocyanides. trans-2-Butenyl isocyanide rearranges without concomitant allylic isomerization to trans-2-butenyl cyanide.Optically active 1-(formyloxymethyl)-2-phenylethyl cyanide is obtained from optically active L-phenylalanine as a new type of chiral pool synthon.
