280745-40-6Relevant academic research and scientific papers
Syntheses of tetrahydroxyazepanes from chiro-inositols and their evaluation as glycosidase inhibitors
Painter, Gavin F.,Eldridge, Paul J.,Falshaw, Andrew
, p. 225 - 232 (2007/10/03)
Two pairs of C2-symmetric tetrahydroxyazepanes [(-), (+)-1 and (-), (+)-2] have been synthesized from the enantiomeric chiro-inositols and evaluated as glycosidase inhibitors. Alternative syntheses of ido-tetrahydroxyazepanes (-)- and (+)-2 fro
Short practical synthesis of (3R,4R,5R,6A)-tetrahydroxyazepane and (3S,4S,5S,6S)-trahydroxyazepane from D- And L-chiroinositol, respectively
Painter, Gavin F.,Falshaw, Andrew
, p. 1157 - 1159 (2007/10/03)
The polyhydroxylated azepanes (3R,4R,5R,6R)-tetrahydroxyazepane (-)-l and (35,45,5S,65)-tetrahydroxyazepane (+)-1 are synthesised from D-and L-c/j/ro-inositol, respectively. Key transformations in the reaction sequence include a glycol-fission reaction wi
